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- W2073163513 abstract "Abstract Phospholipase A did not release mast cell histamine when incubated with isolated rat mast cells in Tyrode solution. the phospholipid breakdown product lysolecithin (10–1000 μg. ml −1 ) did release histamine from mast cells incubated in Tyrode solution. This release was not affected by changes in the incubation temperature. Phospholipase A (30.4 mU.ml −1 −30.4 U.ml −1 ) did release mast cell histamine from isolated mast cells when 188 μg.ml −1 phosphatidylserine or phosphatidylcholine were added to the incubation medium or when phospholipase A and mast cells were incubated in fresh plasma. In this case the release of histamine was dependent on the incubation temperature. Thus lysolecithin appears to release mast cell histamine by a surface active, cytolytic process whereas phospholipase A releases mast cell histamine by a direct enzymic attack on the mast cell." @default.
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- W2073163513 title "Histamine release from rat peritoneal mast cells by phospholipase A. The “activation” of phospholipase a by phospholipids" @default.
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- W2073163513 doi "https://doi.org/10.1016/0006-2952(78)90282-4" @default.
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