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• W2073163711 abstract "Summary The aim of this study was to investigate the correlations of glycated haemoglobin A1c (HbA1c) and glycated albumin ( GA ) with subclinical atherosclerosis in middle‐aged and elderly Chinese populations with impaired glucose regulation ( IGR ). In total, 640 subjects with IGR and no history of cardiovascular disease or carotid artery plaque were recruited for this study (256 men, 384 women; age range, 40–70 years). The carotid intima‐media thickness (C‐ IMT ) measured by carotid ultrasonography was used as an indicator of subclinical atherosclerosis. Increased C‐ IMT was defined as ≥ 0.70 mm (upper quartile). HbA1c and GA were measured with high‐performance liquid chromatography and enzymatic method, respectively. The average HbA1c and GA among all 640 subjects were 5.7 ± 0.3% and 14.0 ± 1.1%, respectively. HbA1c and GA were higher in subjects with increased C‐ IMT than in subjects with normal C‐ IMT (5.8 ± 0.3% vs 5.7 ± 0.3% and 14.2 ± 1.0% vs 13.9 ± 1.1%, respectively; both P < 0.01). Correlation analysis showed that both HbA1c and GA were positively correlated with C‐ IMT ( r = 0.135 and 0.112, respectively; both P < 0.01). Logistic regression analysis revealed that both HbA1c (odds ratio ( OR ), 2.630; 95% confidence interval (95% CI ), 1.401–4.935; P = 0.003) and GA OR , 1.215; 95% CI , 1.008–1.466; P = 0.041) were independent risk factors for increased C‐ IMT . Both HbA1c and GA reflect the risk of subclinical atherosclerosis in middle‐aged and elderly Chinese populations with IGR ." @default.
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• W2073163711 date "2015-06-01" @default.
• W2073163711 modified "2023-10-10" @default.
• W2073163711 title "Associations of glycated haemoglobin A1c and glycated albumin with subclinical atherosclerosis in middle‐aged and elderly Chinese population with impaired glucose regulation" @default.
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• W2073163711 doi "https://doi.org/10.1111/1440-1681.12394" @default.
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