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• W2073193169 abstract "A simple molecular combing method for analysis of biochemical reactions, called the moving droplet method, has been developed. In this method, small droplets containing DNA molecules run down a sloped glass substrate, and this creates a moving interface among the air, droplet, and substrate that stretches the DNA molecules. This method requires a much smaller volume of sample solution than other established combing methods, allowing wider application in various fields. Using this method, λDNA molecules were stretched and absorbed to a glass substrate, and single-molecule analysis of DNA synthesis by DNA polymerases was performed." @default.
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• W2073193169 date "2010-05-01" @default.
• W2073193169 modified "2023-09-23" @default.
• W2073193169 title "A new DNA combing method for biochemical analysis" @default.
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• W2073193169 doi "https://doi.org/10.1016/j.ab.2010.01.021" @default.
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