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- W2073196002 abstract "The preparation of the first library of imidazo[1,2-a]pyridine derivatives on a solid support is described. A sulfone linker strategy was applied in the synthesis. Key steps involved in the solid-phase synthetic procedure include (i) α-haloketone resin formation by sulfinate → sulfone alkylation, (ii) imidazo[1,2-a]pyridine ring formation by treatment with 2-aminopyridine, (iii) sulfone anion alkylation, and (iv) traceless product release by oxidation−elimination. A library of 12 imidazo[1,2-a]pyridines was synthesized." @default.
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- W2073196002 date "2002-10-01" @default.
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- W2073196002 title "Solid-Phase Synthesis of Imidazo[1,2-a]pyridine Using Sodium Benzenesulfinate as a Traceless Linker" @default.
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- W2073196002 doi "https://doi.org/10.1021/ol026797b" @default.
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