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• W2073200745 abstract "Using a combination of differential and density gradient centrifugations, a relatively pure synaptosome fraction was isolated from both septal region and prefrontal cortex of human brains obtained 6–8 h after death. Although postmortem changes were observed in the morphology of the synaptosomes, they were still readily identifiable as synaptosomes and contained high concentrations of acetylcholinesterase and ATPase. Whereas enzymatic activity and morphology of the synaptosomes isolated from the septal region and cortex were essentially the same, acetylcholinesterase activity of those derived from the septal region was about 10 times greater. Of the 3 other distinct fractions obtained from the density gradients and subsequently characterized by electron microscopy and enzyme analysis, one, the membrane fraction, contained numerous profiles of postsynaptic origin." @default.
• W2073200745 created "2016-06-24" @default.
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• W2073200745 date "1972-08-01" @default.
• W2073200745 modified "2023-09-27" @default.
• W2073200745 title "Ganglioside content of membrane fractions from developing pig cerebellar and cerebral cortex separated in a CsCl-sucrose gradient by zonal centrifugation" @default.
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• W2073200745 doi "https://doi.org/10.1016/0006-8993(72)90302-2" @default.
• W2073200745 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5050200" @default.
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