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- W2073201747 abstract "The action of progesterone in mediating the synthesis of avidin by the chick oviduct can be simulated by the intraoviductal instillation of nitrocellulose-trapped RNA from hormonally prepared chick or pigeon oviduct. Similarly, the pigeon oviduct synthesizes avidin in response to chick oviduct RNA. Thus, a heterospecific transfer of hormonal stimulation, through the transfer of progesterone-induced RNA, is demonstrated. The biological activity is lost after digestion by pancreatic ribonuclease. The 50-fold purification achieved by nitrocellulose chromatography of the total RNA preparation suggests that the activity resides in a messenger RNA fraction." @default.
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- W2073201747 date "1973-08-10" @default.
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- W2073201747 title "Progesterone-Dependent Messenger RNA: Heterospecific Activity in vivo" @default.
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- W2073201747 doi "https://doi.org/10.1126/science.181.4099.569" @default.
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