Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073202347> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2073202347 abstract "Efforts in malaria treatment are currently directed towards the discovery and development of new antimalarial compounds. In this way two plants Cochlospermum tinctorium A. Rich. (Cochlospermaceae) and Gardenia sokotensis Hutch (Rubiaceae) traditionally used to treat symptoms of malaria in Burkina Faso were screened for antimalarial activity in vivo with Plasmodium berghei. Dichloromethane extract of Cochlospermum tinctorium and dichloromethane-methanol (7/3v/v) of Gardenia sokotensis showed a promising in vivo antiplasmodial activity with 50% effective dose of 17.59 mg/kg and 115 mg/kg respectively. Water extracts from the two plants showed an interesting antiplasmodial activity of Cochlospermum tinctorium and a weak activity for Gardenia sokotensis. Paradoxically chromatographic fractions issued from the active crude extract of Cochlospermum tinctorium appear less active. The fraction FGs2 of Gardenia has showed a pronounced activity with 42% inhibition rate at 50 mg /kg. These results reflected in part the previous in vitro studies conducted on the two plants. Phytochemical screening revealed mostly the presence of triterpenes, carotenoids and flavonoids more or less in pure state. Keywords: Cochlospermum tinctorium; Gardenia sokotensis; Malaria; Plasmodium berghei African Journal of Traditional, Complementary and Alternative Medicines Vol. 3(4) 2006: 34-41" @default.
- W2073202347 created "2016-06-24" @default.
- W2073202347 creator A5009181657 @default.
- W2073202347 creator A5009474961 @default.
- W2073202347 creator A5021076780 @default.
- W2073202347 creator A5021445911 @default.
- W2073202347 creator A5022935032 @default.
- W2073202347 creator A5062124729 @default.
- W2073202347 creator A5065656174 @default.
- W2073202347 creator A5067550461 @default.
- W2073202347 creator A5091664979 @default.
- W2073202347 date "2006-10-04" @default.
- W2073202347 modified "2023-10-14" @default.
- W2073202347 title "Investigation of antiplasmodial compounds from two plants, <i>Cochlospermum tinctorium</i> A. rich and <i>Gardenia sokotensis</i> Hutch" @default.
- W2073202347 cites W1971178785 @default.
- W2073202347 cites W1973521937 @default.
- W2073202347 cites W2081665674 @default.
- W2073202347 cites W2085828535 @default.
- W2073202347 cites W2088648270 @default.
- W2073202347 cites W2092555711 @default.
- W2073202347 cites W2787325573 @default.
- W2073202347 cites W2811467231 @default.
- W2073202347 cites W326072622 @default.
- W2073202347 doi "https://doi.org/10.4314/ajtcam.v3i4.31175" @default.
- W2073202347 hasPublicationYear "2006" @default.
- W2073202347 type Work @default.
- W2073202347 sameAs 2073202347 @default.
- W2073202347 citedByCount "17" @default.
- W2073202347 countsByYear W20732023472012 @default.
- W2073202347 countsByYear W20732023472013 @default.
- W2073202347 countsByYear W20732023472014 @default.
- W2073202347 countsByYear W20732023472015 @default.
- W2073202347 countsByYear W20732023472016 @default.
- W2073202347 countsByYear W20732023472018 @default.
- W2073202347 countsByYear W20732023472019 @default.
- W2073202347 countsByYear W20732023472021 @default.
- W2073202347 crossrefType "journal-article" @default.
- W2073202347 hasAuthorship W2073202347A5009181657 @default.
- W2073202347 hasAuthorship W2073202347A5009474961 @default.
- W2073202347 hasAuthorship W2073202347A5021076780 @default.
- W2073202347 hasAuthorship W2073202347A5021445911 @default.
- W2073202347 hasAuthorship W2073202347A5022935032 @default.
- W2073202347 hasAuthorship W2073202347A5062124729 @default.
- W2073202347 hasAuthorship W2073202347A5065656174 @default.
- W2073202347 hasAuthorship W2073202347A5067550461 @default.
- W2073202347 hasAuthorship W2073202347A5091664979 @default.
- W2073202347 hasConcept C142724271 @default.
- W2073202347 hasConcept C185592680 @default.
- W2073202347 hasConcept C188947578 @default.
- W2073202347 hasConcept C195475562 @default.
- W2073202347 hasConcept C203014093 @default.
- W2073202347 hasConcept C204787440 @default.
- W2073202347 hasConcept C2777237215 @default.
- W2073202347 hasConcept C2778048844 @default.
- W2073202347 hasConcept C2779904785 @default.
- W2073202347 hasConcept C556039675 @default.
- W2073202347 hasConcept C71924100 @default.
- W2073202347 hasConcept C86803240 @default.
- W2073202347 hasConcept C98274493 @default.
- W2073202347 hasConceptScore W2073202347C142724271 @default.
- W2073202347 hasConceptScore W2073202347C185592680 @default.
- W2073202347 hasConceptScore W2073202347C188947578 @default.
- W2073202347 hasConceptScore W2073202347C195475562 @default.
- W2073202347 hasConceptScore W2073202347C203014093 @default.
- W2073202347 hasConceptScore W2073202347C204787440 @default.
- W2073202347 hasConceptScore W2073202347C2777237215 @default.
- W2073202347 hasConceptScore W2073202347C2778048844 @default.
- W2073202347 hasConceptScore W2073202347C2779904785 @default.
- W2073202347 hasConceptScore W2073202347C556039675 @default.
- W2073202347 hasConceptScore W2073202347C71924100 @default.
- W2073202347 hasConceptScore W2073202347C86803240 @default.
- W2073202347 hasConceptScore W2073202347C98274493 @default.
- W2073202347 hasIssue "4" @default.
- W2073202347 hasLocation W20732023471 @default.
- W2073202347 hasOpenAccess W2073202347 @default.
- W2073202347 hasPrimaryLocation W20732023471 @default.
- W2073202347 hasRelatedWork W1920467315 @default.
- W2073202347 hasRelatedWork W2020052983 @default.
- W2073202347 hasRelatedWork W2048608807 @default.
- W2073202347 hasRelatedWork W2061099686 @default.
- W2073202347 hasRelatedWork W2073202347 @default.
- W2073202347 hasRelatedWork W2106391229 @default.
- W2073202347 hasRelatedWork W2155523753 @default.
- W2073202347 hasRelatedWork W2725037704 @default.
- W2073202347 hasRelatedWork W2947579767 @default.
- W2073202347 hasRelatedWork W4293169518 @default.
- W2073202347 hasVolume "3" @default.
- W2073202347 isParatext "false" @default.
- W2073202347 isRetracted "false" @default.
- W2073202347 magId "2073202347" @default.
- W2073202347 workType "article" @default.