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- W2073225579 abstract "A 61-year-old woman with a 6-year history of diabetes mellitus, hepatitis C, and hypertension presented with skin disease of 2 years’ duration. In 1994, she had developed pruritus and small, ivory-colored, shiny, round maculae scattered over her buttocks and submammary areas that later became atrophic. She underwent a biopsy and was treated with topical corticosteroids and oral antihistamines. Two years later, she developed indurated plaques on her lumbar and abdominal areas (Figure1), with hemorrhagic bullae that gradually produced extensive superficial ulcerations when they ruptured. She subsequently noticed 2 patches of alopecia, atrophy, and ulceration on her scalp (Figure2).There were no lesions involving the vulva or mouth. The findings of the rest of the physical examination were normal. The results of routine blood biochemical and hematologic workup were normal except for the blood glucose and cholesterol levels, which were elevated. Liver function tests showed the following values: aspartate aminotransferase, 43 U/L (reference range, 5-40 U/L); alanine aminotransferase, 98 U/L (reference range, 5-40 U/ L). The results of the autoantibody screen were negative, as were the serologic tests for Borrelia. Erythrocyte sedimentation rate was 31 mm/h. Biopsy specimens were obtained from the scalp and abdominal areas (Figure 3 and Figure 4). What is your diagnosis?" @default.
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- W2073225579 date "1999-01-01" @default.
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- W2073225579 title "Bullous and Hemorrhagic Lesions" @default.
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- W2073225579 doi "https://doi.org/10.1001/archderm.135.1.81" @default.
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