Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073248815> ?p ?o ?g. }
- W2073248815 endingPage "4761" @default.
- W2073248815 startingPage "4755" @default.
- W2073248815 abstract "Approximately one in five neurons is GABAergic in many neocortical areas and species, forming a critical balance between inhibition and excitation in adult circuits. During development, cortical GABAergic neurons are generated in ventral telencephalon and migrate up to developing cortex where the excitatory glutamatergic neurons are born. We ask here: when during development is the adult GABAergic/glutamatergic neuron ratio first established? To answer this question, we have determined the fraction of all neocortical GABAergic neurons that will become inhibitory (GAD67 + ) in mice from embryonic day 10.5 (E10.5) to postnatal day 28 (P28). We find that this fraction is close to 1/5, the adult value, starting from early in corticogenesis (E14.5, when GAD67 + neurons are still migrating tangentially to the cortex) and continuing at the same 1/5 value throughout the remainder of brain development. Thus our data indicate the one-in-five fraction of GABAergic neurons is already established during their neuronal migration and well before significant synapse formation." @default.
- W2073248815 created "2016-06-24" @default.
- W2073248815 creator A5005296029 @default.
- W2073248815 creator A5009203331 @default.
- W2073248815 creator A5012926933 @default.
- W2073248815 creator A5014321400 @default.
- W2073248815 date "2012-04-04" @default.
- W2073248815 modified "2023-10-18" @default.
- W2073248815 title "The Fraction of Cortical GABAergic Neurons Is Constant from Near the Start of Cortical Neurogenesis to Adulthood" @default.
- W2073248815 cites W1715204582 @default.
- W2073248815 cites W1763750158 @default.
- W2073248815 cites W1836312020 @default.
- W2073248815 cites W1904057448 @default.
- W2073248815 cites W1963788090 @default.
- W2073248815 cites W1966492450 @default.
- W2073248815 cites W1971305731 @default.
- W2073248815 cites W1977725794 @default.
- W2073248815 cites W1978212898 @default.
- W2073248815 cites W1981379485 @default.
- W2073248815 cites W1982236792 @default.
- W2073248815 cites W1993636167 @default.
- W2073248815 cites W1993902481 @default.
- W2073248815 cites W1994124220 @default.
- W2073248815 cites W2014104667 @default.
- W2073248815 cites W2014196017 @default.
- W2073248815 cites W2024015768 @default.
- W2073248815 cites W2025603247 @default.
- W2073248815 cites W2034217682 @default.
- W2073248815 cites W2057304270 @default.
- W2073248815 cites W2060923069 @default.
- W2073248815 cites W2062450961 @default.
- W2073248815 cites W2064363302 @default.
- W2073248815 cites W2072139179 @default.
- W2073248815 cites W2084114120 @default.
- W2073248815 cites W2092969675 @default.
- W2073248815 cites W2094234323 @default.
- W2073248815 cites W2098927213 @default.
- W2073248815 cites W2102329408 @default.
- W2073248815 cites W2103828363 @default.
- W2073248815 cites W2104142489 @default.
- W2073248815 cites W2112074923 @default.
- W2073248815 cites W2118077148 @default.
- W2073248815 cites W2125249490 @default.
- W2073248815 cites W2136410726 @default.
- W2073248815 cites W2137059744 @default.
- W2073248815 cites W2141352824 @default.
- W2073248815 cites W2142826449 @default.
- W2073248815 cites W2149671983 @default.
- W2073248815 cites W2151873707 @default.
- W2073248815 cites W2158496649 @default.
- W2073248815 cites W2162499463 @default.
- W2073248815 cites W2208856815 @default.
- W2073248815 doi "https://doi.org/10.1523/jneurosci.6412-11.2012" @default.
- W2073248815 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3325497" @default.
- W2073248815 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22492031" @default.
- W2073248815 hasPublicationYear "2012" @default.
- W2073248815 type Work @default.
- W2073248815 sameAs 2073248815 @default.
- W2073248815 citedByCount "142" @default.
- W2073248815 countsByYear W20732488152012 @default.
- W2073248815 countsByYear W20732488152013 @default.
- W2073248815 countsByYear W20732488152014 @default.
- W2073248815 countsByYear W20732488152015 @default.
- W2073248815 countsByYear W20732488152016 @default.
- W2073248815 countsByYear W20732488152017 @default.
- W2073248815 countsByYear W20732488152018 @default.
- W2073248815 countsByYear W20732488152019 @default.
- W2073248815 countsByYear W20732488152020 @default.
- W2073248815 countsByYear W20732488152021 @default.
- W2073248815 countsByYear W20732488152022 @default.
- W2073248815 countsByYear W20732488152023 @default.
- W2073248815 crossrefType "journal-article" @default.
- W2073248815 hasAuthorship W2073248815A5005296029 @default.
- W2073248815 hasAuthorship W2073248815A5009203331 @default.
- W2073248815 hasAuthorship W2073248815A5012926933 @default.
- W2073248815 hasAuthorship W2073248815A5014321400 @default.
- W2073248815 hasBestOaLocation W20732488151 @default.
- W2073248815 hasConcept C104317684 @default.
- W2073248815 hasConcept C108619961 @default.
- W2073248815 hasConcept C112592302 @default.
- W2073248815 hasConcept C145103041 @default.
- W2073248815 hasConcept C169760540 @default.
- W2073248815 hasConcept C170493617 @default.
- W2073248815 hasConcept C17077164 @default.
- W2073248815 hasConcept C181199279 @default.
- W2073248815 hasConcept C2777348757 @default.
- W2073248815 hasConcept C2778794669 @default.
- W2073248815 hasConcept C2779177108 @default.
- W2073248815 hasConcept C2780597806 @default.
- W2073248815 hasConcept C2780648746 @default.
- W2073248815 hasConcept C2781041448 @default.
- W2073248815 hasConcept C4746552 @default.
- W2073248815 hasConcept C529278444 @default.
- W2073248815 hasConcept C533869091 @default.
- W2073248815 hasConcept C55493867 @default.
- W2073248815 hasConcept C61174792 @default.
- W2073248815 hasConcept C86803240 @default.
- W2073248815 hasConcept C9497952 @default.