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- W2073292142 abstract "Gene-knock-out studies implicate roles of lymphotoxin (LT) α β and LTβR in the initial phase of Peyers patch (PP) organogenesis. We recently identified the requirement of IL-7Rα/γc/Jak3 signal in LTα β production of IL-7Rα+ cells. These observations lead us to a hypothetical model for PP organogenesis with three cellular components. The first is the producer of the ligand for IL-7Rα, which then stimulate the IL-7Rα+ cells to produce LTα β, activating the LTβR+ cells to form an organizing center for PP organogenesis. This model is similar to that of inflammation, suggesting that PP organogenesis is a programmed version of inflammation." @default.
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- W2073292142 date "1998-12-01" @default.
- W2073292142 modified "2023-10-14" @default.
- W2073292142 title "Peyers Patch Organogenesis as a Programmed Inflammation: a Hypothetical Model" @default.
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- W2073292142 doi "https://doi.org/10.1016/s1359-6101(98)00014-8" @default.
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