Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073304812> ?p ?o ?g. }
- W2073304812 endingPage "1075" @default.
- W2073304812 startingPage "1070" @default.
- W2073304812 abstract "Endometriosis is a common gynecologic disease characterized by the ectopic growth of endometrial tissue. In industrialized countries, it affects approximately 10% of women of reproductive age. Its etiology is unclear, but a multifactorial origin is considered to be most plausible. Environmental organochlorinated persistent pollutants, in particular dioxins and polychlorinated biphenyls (PCBs), have been hypothesized to play a role in the disease etiopathogenesis. However, results of studies carried out on humans are conflicting.We evaluated the exposure to organochlorinated persistent pollutants as a risk factor for endometriosis.We conducted a case-control study in Rome on 158 women comprising 80 cases and 78 controls. In all women, serum concentrations of selected non-dioxin-like PCBs (NDL-PCBs) and dioxin-like PCBs (DL-PCBs), 1,1-dichloro-2,2,-bis(4-chlorophenyl)-ethene (p,p'-DDE), and hexachlorobenzene (HCB) were determined by ion-trap mass spectrometry. DR-CALUX bioassay was employed to assess the 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity equivalent (TEQ) concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and DL-PCBs.We found an increased risk of endometriosis for DL-PCB-118 [odds ratio (OR) = 3.79; 95% confidence interval (CI), 1.61-8.91], NDL-PCB-138 (OR = 3.78; 95% CI, 1.60-8.94), NDL-PCB-153 (OR = 4.88; 95% CI, 2.01-11.0), NDL-PCB-170 (OR = 3.52; 95% CI, 1.41-8.79), and the sum of DL-PCBs and NDL-PCBs (OR = 5.63; 95% CI, 2.25-14.10). No significant associations were observed with respect to HCB or to the sum of PCDDs, PCDFs, and DL-PCBs given as total TEQs.The results of this study show that an association exists between increased PCB and p,p'-DDE serum concentrations and the risk of endometriosis." @default.
- W2073304812 created "2016-06-24" @default.
- W2073304812 creator A5001881770 @default.
- W2073304812 creator A5006117668 @default.
- W2073304812 creator A5016670050 @default.
- W2073304812 creator A5018651121 @default.
- W2073304812 creator A5032779620 @default.
- W2073304812 creator A5036790367 @default.
- W2073304812 creator A5065485317 @default.
- W2073304812 creator A5068277944 @default.
- W2073304812 creator A5070572496 @default.
- W2073304812 creator A5074140965 @default.
- W2073304812 creator A5087211984 @default.
- W2073304812 date "2009-07-01" @default.
- W2073304812 modified "2023-10-13" @default.
- W2073304812 title "Endometriosis and Organochlorinated Environmental Pollutants: A Case–Control Study on Italian Women of Reproductive Age" @default.
- W2073304812 cites W1521668645 @default.
- W2073304812 cites W158834731 @default.
- W2073304812 cites W1754070801 @default.
- W2073304812 cites W1891752433 @default.
- W2073304812 cites W1964258150 @default.
- W2073304812 cites W1969059019 @default.
- W2073304812 cites W1974005043 @default.
- W2073304812 cites W1982700658 @default.
- W2073304812 cites W1999133723 @default.
- W2073304812 cites W2000017904 @default.
- W2073304812 cites W2011263735 @default.
- W2073304812 cites W2011725004 @default.
- W2073304812 cites W2014537770 @default.
- W2073304812 cites W2017310817 @default.
- W2073304812 cites W2018800348 @default.
- W2073304812 cites W2021270230 @default.
- W2073304812 cites W2027355065 @default.
- W2073304812 cites W2030199864 @default.
- W2073304812 cites W2045303531 @default.
- W2073304812 cites W2053174345 @default.
- W2073304812 cites W2054034692 @default.
- W2073304812 cites W2059184965 @default.
- W2073304812 cites W2083812486 @default.
- W2073304812 cites W2089014158 @default.
- W2073304812 cites W2093943696 @default.
- W2073304812 cites W2108704542 @default.
- W2073304812 cites W2109125215 @default.
- W2073304812 cites W2115838722 @default.
- W2073304812 cites W2121492292 @default.
- W2073304812 cites W2122887781 @default.
- W2073304812 cites W2127875839 @default.
- W2073304812 cites W2134110886 @default.
- W2073304812 cites W2139546035 @default.
- W2073304812 cites W2140308827 @default.
- W2073304812 cites W2144902034 @default.
- W2073304812 cites W2164269275 @default.
- W2073304812 cites W2165072260 @default.
- W2073304812 cites W2168564335 @default.
- W2073304812 cites W2335194697 @default.
- W2073304812 cites W2412049350 @default.
- W2073304812 cites W2607215535 @default.
- W2073304812 doi "https://doi.org/10.1289/ehp.0800273" @default.
- W2073304812 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2717132" @default.
- W2073304812 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19654915" @default.
- W2073304812 hasPublicationYear "2009" @default.
- W2073304812 type Work @default.
- W2073304812 sameAs 2073304812 @default.
- W2073304812 citedByCount "111" @default.
- W2073304812 countsByYear W20733048122012 @default.
- W2073304812 countsByYear W20733048122013 @default.
- W2073304812 countsByYear W20733048122014 @default.
- W2073304812 countsByYear W20733048122015 @default.
- W2073304812 countsByYear W20733048122016 @default.
- W2073304812 countsByYear W20733048122017 @default.
- W2073304812 countsByYear W20733048122018 @default.
- W2073304812 countsByYear W20733048122019 @default.
- W2073304812 countsByYear W20733048122020 @default.
- W2073304812 countsByYear W20733048122021 @default.
- W2073304812 countsByYear W20733048122022 @default.
- W2073304812 countsByYear W20733048122023 @default.
- W2073304812 crossrefType "journal-article" @default.
- W2073304812 hasAuthorship W2073304812A5001881770 @default.
- W2073304812 hasAuthorship W2073304812A5006117668 @default.
- W2073304812 hasAuthorship W2073304812A5016670050 @default.
- W2073304812 hasAuthorship W2073304812A5018651121 @default.
- W2073304812 hasAuthorship W2073304812A5032779620 @default.
- W2073304812 hasAuthorship W2073304812A5036790367 @default.
- W2073304812 hasAuthorship W2073304812A5065485317 @default.
- W2073304812 hasAuthorship W2073304812A5068277944 @default.
- W2073304812 hasAuthorship W2073304812A5070572496 @default.
- W2073304812 hasAuthorship W2073304812A5074140965 @default.
- W2073304812 hasAuthorship W2073304812A5087211984 @default.
- W2073304812 hasBestOaLocation W20733048121 @default.
- W2073304812 hasConcept C107872376 @default.
- W2073304812 hasConcept C126322002 @default.
- W2073304812 hasConcept C156957248 @default.
- W2073304812 hasConcept C185592680 @default.
- W2073304812 hasConcept C18903297 @default.
- W2073304812 hasConcept C2776044436 @default.
- W2073304812 hasConcept C2777236388 @default.
- W2073304812 hasConcept C2778209978 @default.
- W2073304812 hasConcept C2779423988 @default.