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- W2073307552 abstract "Abstract Bile is the major excretory route for 1,25-dihydroxyvitamin D3 and its metabolites. The amount of radioactivity as a percentage of the total dose found in either urine or combined feces and intestinal contents of bile duct-cannulated rats does not vary with the dose of 1α,25-dihydroxy-[3α-3H]vitamin D3 whereas the percentage of the dose found in bile (24-h collection) increases with increasing dose. When rats were administered 1α,25-dihydroxy-[3α-3H]vitamin D3 and 1α,25-dihydroxy-[26,27-14C]vitamin D3, metabolites with low 14 C 3 H (indicative of side chain-cleaved metabolites) were detected in bile, but not in either the urine or combined feces and intestinal contents. Bile had the lowest 14 C 3 H ratio 8–12 h after the dose." @default.
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- W2073307552 date "1980-11-01" @default.
- W2073307552 modified "2023-10-14" @default.
- W2073307552 title "Excretion of metabolites of 1α,25-dihydroxyvitamin D3 in rat bile" @default.
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- W2073307552 doi "https://doi.org/10.1016/0003-9861(80)90096-x" @default.
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