FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073356803> ?p ?o ?g. }

• W2073356803 endingPage "252" @default.
• W2073356803 startingPage "244" @default.
• W2073356803 abstract "Host genetic factors are emerging as key determinants of disease risk for many cancers. Identifying candidate genes is a major challenge that has to stem from a profound understanding of the pathophysiology of the disease. The Toll-like receptors are important members of the host's innate immune response and their genes have been found to be polymorphic. This genetic variation allows for a more intricate repertoire that enables the host to withstand microbial challenges. While this may be advantageous on a population level, there may be less favourable outcomes for individuals that harbour certain genotypes associated with excessive immune activation and inflammatory drive. The damage is often collateral and is manifest in organs where this chronic inflammation alters normal physiology. A classic example of this paradigm is the Helicobacter pylori-induced gastric cancer model. Another emerging model is prostate cancer where Toll-like receptor polymorphisms have also been found to play a role. In this review, we discuss polymorphisms in Toll-like receptors and give an insight into how they may influence risk of cancer." @default.
• W2073356803 created "2016-06-24" @default.
• W2073356803 creator A5001047274 @default.
• W2073356803 creator A5013881914 @default.
• W2073356803 creator A5058258257 @default.
• W2073356803 date "2008-01-07" @default.
• W2073356803 modified "2023-10-05" @default.
• W2073356803 title "Polymorphisms in Toll-like receptor genes and risk of cancer" @default.
• W2073356803 cites W112824597 @default.
• W2073356803 cites W1489842152 @default.
• W2073356803 cites W1520365933 @default.
• W2073356803 cites W1551600243 @default.
• W2073356803 cites W1582490802 @default.
• W2073356803 cites W1905843327 @default.
• W2073356803 cites W1965341361 @default.
• W2073356803 cites W1966919135 @default.
• W2073356803 cites W1967918248 @default.
• W2073356803 cites W1968143482 @default.
• W2073356803 cites W1969408372 @default.
• W2073356803 cites W1984744520 @default.
• W2073356803 cites W1986976274 @default.
• W2073356803 cites W1989856701 @default.
• W2073356803 cites W1990142540 @default.
• W2073356803 cites W1992945893 @default.
• W2073356803 cites W1994458586 @default.
• W2073356803 cites W1995577330 @default.
• W2073356803 cites W1996573346 @default.
• W2073356803 cites W2001921163 @default.
• W2073356803 cites W2003322692 @default.
• W2073356803 cites W2005670414 @default.
• W2073356803 cites W2008003223 @default.
• W2073356803 cites W2009107334 @default.
• W2073356803 cites W2010219741 @default.
• W2073356803 cites W2010397777 @default.
• W2073356803 cites W2011560892 @default.
• W2073356803 cites W2020830322 @default.
• W2073356803 cites W2022948175 @default.
• W2073356803 cites W2033051264 @default.
• W2073356803 cites W2038486513 @default.
• W2073356803 cites W2040853949 @default.
• W2073356803 cites W2046454404 @default.
• W2073356803 cites W2057593547 @default.
• W2073356803 cites W2059724367 @default.
• W2073356803 cites W2062579269 @default.
• W2073356803 cites W2063732910 @default.
• W2073356803 cites W2067613544 @default.
• W2073356803 cites W2088540732 @default.
• W2073356803 cites W2091229884 @default.
• W2073356803 cites W2092531978 @default.
• W2073356803 cites W2100649505 @default.
• W2073356803 cites W2102794755 @default.
• W2073356803 cites W2107674270 @default.
• W2073356803 cites W2112223832 @default.
• W2073356803 cites W2121656093 @default.
• W2073356803 cites W2133449490 @default.
• W2073356803 cites W2136143589 @default.
• W2073356803 cites W2136157960 @default.
• W2073356803 cites W2136414961 @default.
• W2073356803 cites W2140283236 @default.
• W2073356803 cites W2144648254 @default.
• W2073356803 cites W2145708021 @default.
• W2073356803 cites W2150794592 @default.
• W2073356803 cites W2157339124 @default.
• W2073356803 cites W2168112559 @default.
• W2073356803 cites W2170349437 @default.
• W2073356803 cites W2170681637 @default.
• W2073356803 cites W2172258104 @default.
• W2073356803 cites W2323815710 @default.
• W2073356803 doi "https://doi.org/10.1038/sj.onc.1210912" @default.
• W2073356803 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18176606" @default.
• W2073356803 hasPublicationYear "2008" @default.
• W2073356803 type Work @default.
• W2073356803 sameAs 2073356803 @default.
• W2073356803 citedByCount "211" @default.
• W2073356803 countsByYear W20733568032012 @default.
• W2073356803 countsByYear W20733568032013 @default.
• W2073356803 countsByYear W20733568032014 @default.
• W2073356803 countsByYear W20733568032015 @default.
• W2073356803 countsByYear W20733568032016 @default.
• W2073356803 countsByYear W20733568032017 @default.
• W2073356803 countsByYear W20733568032018 @default.
• W2073356803 countsByYear W20733568032019 @default.
• W2073356803 countsByYear W20733568032020 @default.
• W2073356803 countsByYear W20733568032021 @default.
• W2073356803 countsByYear W20733568032022 @default.
• W2073356803 countsByYear W20733568032023 @default.
• W2073356803 crossrefType "journal-article" @default.
• W2073356803 hasAuthorship W2073356803A5001047274 @default.
• W2073356803 hasAuthorship W2073356803A5013881914 @default.
• W2073356803 hasAuthorship W2073356803A5058258257 @default.
• W2073356803 hasBestOaLocation W20733568031 @default.
• W2073356803 hasConcept C104317684 @default.
• W2073356803 hasConcept C121608353 @default.
• W2073356803 hasConcept C126322002 @default.
• W2073356803 hasConcept C136449434 @default.
• W2073356803 hasConcept C144024400 @default.
• W2073356803 hasConcept C149923435 @default.
• W2073356803 hasConcept C170493617 @default.

• next