Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073357387> ?p ?o ?g. }
- W2073357387 endingPage "100" @default.
- W2073357387 startingPage "87" @default.
- W2073357387 abstract "Using pHluorin-tagged synaptic vesicle proteins we have examined the partitioning of these probes into recycling and nonrecycling pools at hippocampal nerve terminals in cell culture. Our studies show that for three of the major synaptic vesicle components, vGlut-1, VAMP-2, and Synaptotagmin I, ~50–60% of the tagged protein appears in a recycling pool that responds readily to sustained action potential stimulation by mobilizing and fusing with the plasma membrane, while the remainder is targeted to a nonrecycling, acidic compartment. The fraction of recycling and nonrecycling (or resting) pools varied significantly across boutons within an individual axon, from 100% resting (silent) to 100% recycling. Single-bouton bleaching studies show that recycling and resting pools are dynamic and exchange between synaptic boutons. The quantitative parameters that can be extracted with the approaches outlined here should help elucidate the potential functional role of the resting vesicle pool." @default.
- W2073357387 created "2016-06-24" @default.
- W2073357387 creator A5008547059 @default.
- W2073357387 creator A5085378517 @default.
- W2073357387 date "2008-08-01" @default.
- W2073357387 modified "2023-09-30" @default.
- W2073357387 title "A heterogeneous “resting” pool of synaptic vesicles that is dynamically interchanged across boutons in mammalian CNS synapses" @default.
- W2073357387 cites W1498241934 @default.
- W2073357387 cites W1498924480 @default.
- W2073357387 cites W1513649738 @default.
- W2073357387 cites W1562455864 @default.
- W2073357387 cites W1885712480 @default.
- W2073357387 cites W1927867726 @default.
- W2073357387 cites W1965793946 @default.
- W2073357387 cites W1965893090 @default.
- W2073357387 cites W1973320665 @default.
- W2073357387 cites W1975086853 @default.
- W2073357387 cites W1975136077 @default.
- W2073357387 cites W1975565947 @default.
- W2073357387 cites W1978842225 @default.
- W2073357387 cites W1980548298 @default.
- W2073357387 cites W1984766476 @default.
- W2073357387 cites W1989341569 @default.
- W2073357387 cites W1990646890 @default.
- W2073357387 cites W1990955856 @default.
- W2073357387 cites W1995300675 @default.
- W2073357387 cites W2008643711 @default.
- W2073357387 cites W2012851040 @default.
- W2073357387 cites W2016166286 @default.
- W2073357387 cites W2017506170 @default.
- W2073357387 cites W2019016101 @default.
- W2073357387 cites W2024966724 @default.
- W2073357387 cites W2029198617 @default.
- W2073357387 cites W2051620676 @default.
- W2073357387 cites W2058907411 @default.
- W2073357387 cites W2069536209 @default.
- W2073357387 cites W2070163775 @default.
- W2073357387 cites W2074688705 @default.
- W2073357387 cites W2084864774 @default.
- W2073357387 cites W2087447309 @default.
- W2073357387 cites W2089157578 @default.
- W2073357387 cites W2098434647 @default.
- W2073357387 cites W2126656642 @default.
- W2073357387 cites W2126947320 @default.
- W2073357387 cites W2129696839 @default.
- W2073357387 cites W2135719485 @default.
- W2073357387 cites W2144447780 @default.
- W2073357387 cites W2169799322 @default.
- W2073357387 cites W4231136244 @default.
- W2073357387 cites W4300875606 @default.
- W2073357387 doi "https://doi.org/10.1007/s11068-008-9030-y" @default.
- W2073357387 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2924874" @default.
- W2073357387 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18941900" @default.
- W2073357387 hasPublicationYear "2008" @default.
- W2073357387 type Work @default.
- W2073357387 sameAs 2073357387 @default.
- W2073357387 citedByCount "74" @default.
- W2073357387 countsByYear W20733573872012 @default.
- W2073357387 countsByYear W20733573872013 @default.
- W2073357387 countsByYear W20733573872014 @default.
- W2073357387 countsByYear W20733573872015 @default.
- W2073357387 countsByYear W20733573872016 @default.
- W2073357387 countsByYear W20733573872017 @default.
- W2073357387 countsByYear W20733573872019 @default.
- W2073357387 countsByYear W20733573872020 @default.
- W2073357387 countsByYear W20733573872021 @default.
- W2073357387 countsByYear W20733573872022 @default.
- W2073357387 countsByYear W20733573872023 @default.
- W2073357387 crossrefType "journal-article" @default.
- W2073357387 hasAuthorship W2073357387A5008547059 @default.
- W2073357387 hasAuthorship W2073357387A5085378517 @default.
- W2073357387 hasBestOaLocation W20733573871 @default.
- W2073357387 hasConcept C111368507 @default.
- W2073357387 hasConcept C12554922 @default.
- W2073357387 hasConcept C127313418 @default.
- W2073357387 hasConcept C127445978 @default.
- W2073357387 hasConcept C130316041 @default.
- W2073357387 hasConcept C148762608 @default.
- W2073357387 hasConcept C148785051 @default.
- W2073357387 hasConcept C169760540 @default.
- W2073357387 hasConcept C185592680 @default.
- W2073357387 hasConcept C203635412 @default.
- W2073357387 hasConcept C24998067 @default.
- W2073357387 hasConcept C2779530196 @default.
- W2073357387 hasConcept C2909695770 @default.
- W2073357387 hasConcept C41625074 @default.
- W2073357387 hasConcept C55493867 @default.
- W2073357387 hasConcept C86473631 @default.
- W2073357387 hasConcept C86803240 @default.
- W2073357387 hasConcept C95444343 @default.
- W2073357387 hasConceptScore W2073357387C111368507 @default.
- W2073357387 hasConceptScore W2073357387C12554922 @default.
- W2073357387 hasConceptScore W2073357387C127313418 @default.
- W2073357387 hasConceptScore W2073357387C127445978 @default.
- W2073357387 hasConceptScore W2073357387C130316041 @default.
- W2073357387 hasConceptScore W2073357387C148762608 @default.
- W2073357387 hasConceptScore W2073357387C148785051 @default.
- W2073357387 hasConceptScore W2073357387C169760540 @default.