Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073368150> ?p ?o ?g. }
- W2073368150 endingPage "6161" @default.
- W2073368150 startingPage "6154" @default.
- W2073368150 abstract "Ceramidases are key regulators of cell fate. The biochemistry of different ceramidases and of their substrate ceramide appears to be complex, mainly due to specific biophysical characteristics at the water-membrane interface. In the present study, we describe the design and synthesis of a set of fluorescently labeled ceramides as substrates for acid and neutral ceramidases. For the first time we have replaced the commonly used polar NBD-dye with the lipophilic Nile Red (NR) dye. Analysis of kinetic data reveal that although both the dyes do not have any noticeable preference for the substitution at acyl or sphingosine (Sph) part in ceramide towards hydrolysis by acid ceramidase, the ceramides with acyl-substituted NBD and Sph-substituted NR dyes have been found to be a better substrate for neutral ceramidase." @default.
- W2073368150 created "2016-06-24" @default.
- W2073368150 creator A5000581632 @default.
- W2073368150 creator A5018401208 @default.
- W2073368150 creator A5049811136 @default.
- W2073368150 creator A5054577999 @default.
- W2073368150 date "2012-10-01" @default.
- W2073368150 modified "2023-09-23" @default.
- W2073368150 title "Novel fluorescent ceramide derivatives for probing ceramidase substrate specificity" @default.
- W2073368150 cites W1517500969 @default.
- W2073368150 cites W1522304947 @default.
- W2073368150 cites W1583161747 @default.
- W2073368150 cites W1594095562 @default.
- W2073368150 cites W1815075576 @default.
- W2073368150 cites W1841593942 @default.
- W2073368150 cites W1966452335 @default.
- W2073368150 cites W1968784427 @default.
- W2073368150 cites W1976588883 @default.
- W2073368150 cites W1978391650 @default.
- W2073368150 cites W1985233589 @default.
- W2073368150 cites W1988215673 @default.
- W2073368150 cites W1988374405 @default.
- W2073368150 cites W1997467660 @default.
- W2073368150 cites W1997900152 @default.
- W2073368150 cites W1999015381 @default.
- W2073368150 cites W2008279103 @default.
- W2073368150 cites W2013608724 @default.
- W2073368150 cites W2014923090 @default.
- W2073368150 cites W2019174969 @default.
- W2073368150 cites W2022770236 @default.
- W2073368150 cites W2025338956 @default.
- W2073368150 cites W2027027613 @default.
- W2073368150 cites W2031236360 @default.
- W2073368150 cites W2038274403 @default.
- W2073368150 cites W2039261865 @default.
- W2073368150 cites W2039321321 @default.
- W2073368150 cites W2046340987 @default.
- W2073368150 cites W2053989476 @default.
- W2073368150 cites W2058006650 @default.
- W2073368150 cites W2058901028 @default.
- W2073368150 cites W2064032523 @default.
- W2073368150 cites W2064062755 @default.
- W2073368150 cites W2064601706 @default.
- W2073368150 cites W2065580563 @default.
- W2073368150 cites W2066287839 @default.
- W2073368150 cites W2076691840 @default.
- W2073368150 cites W2086522442 @default.
- W2073368150 cites W2089440412 @default.
- W2073368150 cites W2094250733 @default.
- W2073368150 cites W2104767801 @default.
- W2073368150 cites W2106121689 @default.
- W2073368150 cites W2116583338 @default.
- W2073368150 cites W2121936687 @default.
- W2073368150 cites W2134579258 @default.
- W2073368150 cites W2137149853 @default.
- W2073368150 cites W2139698604 @default.
- W2073368150 cites W2142833551 @default.
- W2073368150 cites W2147454663 @default.
- W2073368150 cites W2162335724 @default.
- W2073368150 cites W2165756111 @default.
- W2073368150 cites W2403499588 @default.
- W2073368150 cites W2949190300 @default.
- W2073368150 cites W4233378160 @default.
- W2073368150 cites W4244540082 @default.
- W2073368150 doi "https://doi.org/10.1016/j.bmc.2012.08.035" @default.
- W2073368150 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22989909" @default.
- W2073368150 hasPublicationYear "2012" @default.
- W2073368150 type Work @default.
- W2073368150 sameAs 2073368150 @default.
- W2073368150 citedByCount "25" @default.
- W2073368150 countsByYear W20733681502013 @default.
- W2073368150 countsByYear W20733681502014 @default.
- W2073368150 countsByYear W20733681502015 @default.
- W2073368150 countsByYear W20733681502016 @default.
- W2073368150 countsByYear W20733681502017 @default.
- W2073368150 countsByYear W20733681502018 @default.
- W2073368150 countsByYear W20733681502019 @default.
- W2073368150 countsByYear W20733681502020 @default.
- W2073368150 countsByYear W20733681502022 @default.
- W2073368150 countsByYear W20733681502023 @default.
- W2073368150 crossrefType "journal-article" @default.
- W2073368150 hasAuthorship W2073368150A5000581632 @default.
- W2073368150 hasAuthorship W2073368150A5018401208 @default.
- W2073368150 hasAuthorship W2073368150A5049811136 @default.
- W2073368150 hasAuthorship W2073368150A5054577999 @default.
- W2073368150 hasConcept C111368507 @default.
- W2073368150 hasConcept C121332964 @default.
- W2073368150 hasConcept C127313418 @default.
- W2073368150 hasConcept C170493617 @default.
- W2073368150 hasConcept C185592680 @default.
- W2073368150 hasConcept C190283241 @default.
- W2073368150 hasConcept C2777289219 @default.
- W2073368150 hasConcept C2777851122 @default.
- W2073368150 hasConcept C2778086801 @default.
- W2073368150 hasConcept C2778703144 @default.
- W2073368150 hasConcept C41625074 @default.
- W2073368150 hasConcept C55493867 @default.
- W2073368150 hasConcept C61322309 @default.