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• W2073374773 abstract "The mechanisms by which cyclins promote mammalian cell cycle progression have been a topic of intense investigation over the last decade. We previously described an interaction between D-type cyclins and A-kinase anchoring protein, AKAP95. Here, we demonstrate that AKAP95 can also bind cyclin E1. Association between AKAP95 and cyclins is displaced by CDKs. We show that these G(1)/S cyclins can interact with RII subunit of PKAalpha through AKAP95. The presence of alternate complexes cyclin-CDK and cyclin D/E-AKAP95-PKA.RIIalpha suggest different roles of G(1)/S cyclins and a wider biological importance of these interactions in cells." @default.
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• W2073374773 date "2006-05-12" @default.
• W2073374773 modified "2023-09-27" @default.
• W2073374773 title "G1/S Cyclins Interact with Regulatory Subunit of PKA via A-Kinase Anchoring Protein, AKAP95" @default.
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• W2073374773 doi "https://doi.org/10.4161/cc.5.11.2802" @default.
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