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• W2073378157 startingPage "966" @default.
• W2073378157 abstract "The diverse biological actions of insulin and insulin‐like growth factor I (IGF‐I) are initiated by binding of the polypeptides to their respective cell surface tyrosine kinase receptors. These activated receptors phosphorylate a series of endogenous substrates on tyrosine, amongst which the insulin receptor substrate (IRS) proteins are the best characterized. Their phosphotyrosine‐containing motifs become binding sites for Src homology 2 (SH2) domains on proteins such as SH2 domain‐containing protein‐tyrosine‐phosphatase (SHP)‐2/Syp, growth factor receptor bound‐2 protien, (Grb‐2), and phosphatidyl inositol 3 kinase (PI3 kinase), which participate in activation of specific signaling cascades. However, the IRS molecules are not only platforms for signaling molecules, they also orchestrate the generation of signal specificity, integration of signals induced by several extracellular stimuli, and signal termination and modulation. An extensive review is beyond the scope of the present article, which will be centered on our own contribution and reflect our biases." @default.
• W2073378157 created "2016-06-24" @default.
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• W2073378157 date "2001-11-01" @default.
• W2073378157 modified "2023-10-18" @default.
• W2073378157 title "Surfing the insulin signaling web" @default.
• W2073378157 cites W1488478985 @default.
• W2073378157 cites W1536641330 @default.
• W2073378157 cites W1543324954 @default.
• W2073378157 cites W1562079260 @default.
• W2073378157 cites W1570362997 @default.
• W2073378157 cites W1570629413 @default.
• W2073378157 cites W1620663301 @default.
• W2073378157 cites W1668039320 @default.
• W2073378157 cites W1697523131 @default.
• W2073378157 cites W1726652071 @default.
• W2073378157 cites W1931082872 @default.
• W2073378157 cites W1963632439 @default.
• W2073378157 cites W1963696964 @default.
• W2073378157 cites W1967525449 @default.
• W2073378157 cites W1977011921 @default.
• W2073378157 cites W1977128714 @default.
• W2073378157 cites W1978046076 @default.
• W2073378157 cites W1981043027 @default.
• W2073378157 cites W1985113364 @default.
• W2073378157 cites W1986156442 @default.
• W2073378157 cites W1986758681 @default.
• W2073378157 cites W1988870963 @default.
• W2073378157 cites W1993672117 @default.
• W2073378157 cites W1996560248 @default.
• W2073378157 cites W1997859241 @default.
• W2073378157 cites W2002398354 @default.
• W2073378157 cites W2004593694 @default.
• W2073378157 cites W2007217993 @default.
• W2073378157 cites W2013523350 @default.
• W2073378157 cites W2016519406 @default.
• W2073378157 cites W2018917333 @default.
• W2073378157 cites W2024029655 @default.
• W2073378157 cites W2024059382 @default.
• W2073378157 cites W2027360957 @default.
• W2073378157 cites W2028970216 @default.
• W2073378157 cites W2031504013 @default.
• W2073378157 cites W2032949521 @default.
• W2073378157 cites W2033330574 @default.
• W2073378157 cites W2033429522 @default.
• W2073378157 cites W2038973974 @default.
• W2073378157 cites W2043590500 @default.
• W2073378157 cites W2045726368 @default.
• W2073378157 cites W2046933787 @default.
• W2073378157 cites W2048145216 @default.
• W2073378157 cites W2049761828 @default.
• W2073378157 cites W2049875806 @default.
• W2073378157 cites W2050478738 @default.
• W2073378157 cites W2055639794 @default.
• W2073378157 cites W2056045316 @default.
• W2073378157 cites W2056734858 @default.
• W2073378157 cites W2061127969 @default.
• W2073378157 cites W2062596469 @default.
• W2073378157 cites W2064801081 @default.
• W2073378157 cites W2066569500 @default.
• W2073378157 cites W2069116251 @default.
• W2073378157 cites W2070082950 @default.
• W2073378157 cites W2073926725 @default.
• W2073378157 cites W2077163123 @default.
• W2073378157 cites W2082390264 @default.
• W2073378157 cites W2083434885 @default.
• W2073378157 cites W2086082646 @default.
• W2073378157 cites W2093670935 @default.
• W2073378157 cites W2095252238 @default.
• W2073378157 cites W2096299662 @default.
• W2073378157 cites W2103174300 @default.
• W2073378157 cites W2106415942 @default.
• W2073378157 cites W2107664641 @default.
• W2073378157 cites W2109046004 @default.
• W2073378157 cites W2129750908 @default.
• W2073378157 cites W2132647577 @default.
• W2073378157 cites W2135096442 @default.
• W2073378157 cites W2138352001 @default.
• W2073378157 cites W2139907742 @default.
• W2073378157 cites W2140793658 @default.
• W2073378157 cites W2147825853 @default.
• W2073378157 cites W2148258829 @default.
• W2073378157 cites W2154713680 @default.
• W2073378157 cites W2161071101 @default.
• W2073378157 cites W2163101309 @default.
• W2073378157 cites W2164965551 @default.

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