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- W2073394329 abstract "Individuals who exhibit exaggerated blood pressure reactions to psychological stressors are at risk for hypertension, ventricular hypertrophy, and premature atherosclerosis; however, the neural systems mediating exaggerated blood pressure reactivity and associated cardiovascular risk in humans remain poorly defined. Animal models indicate that the amygdala orchestrates stressor-evoked blood pressure reactions via reciprocal signaling with corticolimbic and brainstem cardiovascular-regulatory circuits. Based on these models, we used a multimodal neuroimaging approach to determine whether human individual differences in stressor-evoked blood pressure reactivity vary with amygdala activation, gray matter volume, and functional connectivity with corticolimbic and brainstem areas implicated in stressor processing and cardiovascular regulation. We monitored mean arterial pressure (MAP) and concurrent functional magnetic resonance imaging BOLD signal changes in healthy young individuals while they completed a Stroop color-word stressor task, validated previously in epidemiological studies of cardiovascular risk. Individuals exhibiting greater stressor-evoked MAP reactivity showed (1) greater amygdala activation, (2) lower amygdala gray matter volume, and (3) stronger positive functional connectivity between the amygdala and perigenual anterior cingulate cortex and brainstem pons. Individual differences in amygdala activation, gray matter volume, and functional connectivity with corticolimbic and brainstem circuits may partly underpin cardiovascular disease risk by impacting stressor-evoked blood pressure reactivity." @default.
- W2073394329 created "2016-06-24" @default.
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- W2073394329 date "2008-01-23" @default.
- W2073394329 modified "2023-10-04" @default.
- W2073394329 title "Individual Differences in Stressor-Evoked Blood Pressure Reactivity Vary with Activation, Volume, and Functional Connectivity of the Amygdala" @default.
- W2073394329 cites W1512847190 @default.
- W2073394329 cites W1665095741 @default.
- W2073394329 cites W1694363227 @default.
- W2073394329 cites W1965913971 @default.
- W2073394329 cites W1966117108 @default.
- W2073394329 cites W1969032152 @default.
- W2073394329 cites W1971798413 @default.
- W2073394329 cites W1985349171 @default.
- W2073394329 cites W1985715468 @default.
- W2073394329 cites W1986320798 @default.
- W2073394329 cites W1996117824 @default.
- W2073394329 cites W1997763915 @default.
- W2073394329 cites W1999201555 @default.
- W2073394329 cites W1999805211 @default.
- W2073394329 cites W2001362807 @default.
- W2073394329 cites W2002958204 @default.
- W2073394329 cites W2009140566 @default.
- W2073394329 cites W2010123047 @default.
- W2073394329 cites W2016944059 @default.
- W2073394329 cites W2017089787 @default.
- W2073394329 cites W2017748947 @default.
- W2073394329 cites W2019993815 @default.
- W2073394329 cites W2021031321 @default.
- W2073394329 cites W2026720425 @default.
- W2073394329 cites W2028850601 @default.
- W2073394329 cites W2042280485 @default.
- W2073394329 cites W2044278316 @default.
- W2073394329 cites W2044634376 @default.
- W2073394329 cites W2046179952 @default.
- W2073394329 cites W2048678006 @default.
- W2073394329 cites W2057130871 @default.
- W2073394329 cites W2063535919 @default.
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- W2073394329 cites W2070993310 @default.
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- W2073394329 cites W2078204079 @default.
- W2073394329 cites W2093093078 @default.
- W2073394329 cites W2095438393 @default.
- W2073394329 cites W2095888968 @default.
- W2073394329 cites W2101562854 @default.
- W2073394329 cites W2102748276 @default.
- W2073394329 cites W2105947467 @default.
- W2073394329 cites W2106705508 @default.
- W2073394329 cites W2111464173 @default.
- W2073394329 cites W2116649573 @default.
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- W2073394329 cites W2118421222 @default.
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- W2073394329 cites W2125823313 @default.
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- W2073394329 doi "https://doi.org/10.1523/jneurosci.3606-07.2008" @default.
- W2073394329 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2526972" @default.
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