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- W2073418631 abstract "Candida albicans is the most common human fungal pathogen. Many organisms, including C. albicans, secrete glucanases under different environmental conditions. Here, we report a novel role for beta-1, 3- glucanase in inducing Candida albicans to form filaments at 22°C and enhancing filamentation at 37°C in nutrient-rich medium. Quorum sensing, the efg1-signaling and cek1 MAP kinase pathways are involved in this process. Our data suggest that the natural antifungal agent beta-glucanase may support morphologic transformation of Candida albicans at a wide range of ambient temperatures." @default.
- W2073418631 created "2016-06-24" @default.
- W2073418631 creator A5017105081 @default.
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- W2073418631 date "2013-05-30" @default.
- W2073418631 modified "2023-10-06" @default.
- W2073418631 title "Glucanase Induces Filamentation of the Fungal Pathogen Candida albicans" @default.
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- W2073418631 doi "https://doi.org/10.1371/journal.pone.0063736" @default.
- W2073418631 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3667860" @default.
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