Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073442331> ?p ?o ?g. }
- W2073442331 endingPage "221" @default.
- W2073442331 startingPage "214" @default.
- W2073442331 abstract "The theoretical impossibility of polyploidy in mammals was overturned by the discovery of tetraploidy in the red vizcacha rat, Tympanoctomys barrerae (2n = 102). As a consequence of genome duplication, remarkably increased cell dimensions are observed in the spermatozoa and in different somatic cell lines of this species. Locus duplication had been previously demonstrated by in situ PCR and Southern blot analysis of single-copy genes. Here, we corroborate duplication of loci in multiple-copy (major rDNAs) and single-copy (Hoxc8) genes by fluorescence in situ hybridization. We also demonstrate that nucleolar dominance, a large-scale epigenetic silencing phenomenon characteristic of allopolyploids, explains the presence of only one Ag-NOR chromosome pair in T. barrerae. Nucleolar dominance, together with the chromosomal heteromorphism detected in the G-banding pattern and synaptonemal complexes of the species’ diploid-like meiosis, consistently indicates allotetraploidy. Allotetraploidization can coherently explain the peculiarities of gene silencing, cell dimensions, and karyotypic features of T. barrerae that remain unexplained by assuming diploidy and a large genome size attained by the dispersion of repetitive sequences." @default.
- W2073442331 created "2016-06-24" @default.
- W2073442331 creator A5009567429 @default.
- W2073442331 creator A5025046371 @default.
- W2073442331 creator A5089433588 @default.
- W2073442331 date "2006-08-01" @default.
- W2073442331 modified "2023-09-27" @default.
- W2073442331 title "Molecular cytogenetics and allotetraploidy in the red vizcacha rat, Tympanoctomys barrerae (Rodentia, Octodontidae)" @default.
- W2073442331 cites W1554669004 @default.
- W2073442331 cites W1854399242 @default.
- W2073442331 cites W1914616932 @default.
- W2073442331 cites W1966185068 @default.
- W2073442331 cites W1968883815 @default.
- W2073442331 cites W1972628065 @default.
- W2073442331 cites W1974028613 @default.
- W2073442331 cites W1976390792 @default.
- W2073442331 cites W1977961184 @default.
- W2073442331 cites W1988652159 @default.
- W2073442331 cites W1990743073 @default.
- W2073442331 cites W1999455461 @default.
- W2073442331 cites W2001670067 @default.
- W2073442331 cites W2001729273 @default.
- W2073442331 cites W2005350877 @default.
- W2073442331 cites W2005551491 @default.
- W2073442331 cites W2006873092 @default.
- W2073442331 cites W2007529428 @default.
- W2073442331 cites W2020139042 @default.
- W2073442331 cites W2025943589 @default.
- W2073442331 cites W2027477602 @default.
- W2073442331 cites W2029587232 @default.
- W2073442331 cites W2043372425 @default.
- W2073442331 cites W2046357315 @default.
- W2073442331 cites W2051741276 @default.
- W2073442331 cites W2051781993 @default.
- W2073442331 cites W2054534446 @default.
- W2073442331 cites W2056580641 @default.
- W2073442331 cites W2062884914 @default.
- W2073442331 cites W2065793685 @default.
- W2073442331 cites W2066519709 @default.
- W2073442331 cites W2073509062 @default.
- W2073442331 cites W2083925192 @default.
- W2073442331 cites W2084139224 @default.
- W2073442331 cites W2086687656 @default.
- W2073442331 cites W2109824289 @default.
- W2073442331 cites W2116876658 @default.
- W2073442331 cites W2125032568 @default.
- W2073442331 cites W2126867247 @default.
- W2073442331 cites W2140331446 @default.
- W2073442331 cites W2145032210 @default.
- W2073442331 cites W2146789847 @default.
- W2073442331 cites W2156340374 @default.
- W2073442331 cites W2157991399 @default.
- W2073442331 cites W2159735183 @default.
- W2073442331 cites W2161139630 @default.
- W2073442331 cites W2161939161 @default.
- W2073442331 cites W2164597927 @default.
- W2073442331 cites W2166483716 @default.
- W2073442331 cites W2168557059 @default.
- W2073442331 cites W2172004139 @default.
- W2073442331 cites W2319777983 @default.
- W2073442331 cites W2333912138 @default.
- W2073442331 cites W2422089569 @default.
- W2073442331 cites W2588184732 @default.
- W2073442331 cites W3007529384 @default.
- W2073442331 cites W4235131565 @default.
- W2073442331 doi "https://doi.org/10.1016/j.ygeno.2006.02.010" @default.
- W2073442331 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16580173" @default.
- W2073442331 hasPublicationYear "2006" @default.
- W2073442331 type Work @default.
- W2073442331 sameAs 2073442331 @default.
- W2073442331 citedByCount "46" @default.
- W2073442331 countsByYear W20734423312012 @default.
- W2073442331 countsByYear W20734423312013 @default.
- W2073442331 countsByYear W20734423312014 @default.
- W2073442331 countsByYear W20734423312015 @default.
- W2073442331 countsByYear W20734423312016 @default.
- W2073442331 countsByYear W20734423312017 @default.
- W2073442331 countsByYear W20734423312018 @default.
- W2073442331 countsByYear W20734423312019 @default.
- W2073442331 countsByYear W20734423312020 @default.
- W2073442331 countsByYear W20734423312023 @default.
- W2073442331 crossrefType "journal-article" @default.
- W2073442331 hasAuthorship W2073442331A5009567429 @default.
- W2073442331 hasAuthorship W2073442331A5025046371 @default.
- W2073442331 hasAuthorship W2073442331A5089433588 @default.
- W2073442331 hasBestOaLocation W20734423311 @default.
- W2073442331 hasConcept C104317684 @default.
- W2073442331 hasConcept C133307689 @default.
- W2073442331 hasConcept C141231307 @default.
- W2073442331 hasConcept C143191323 @default.
- W2073442331 hasConcept C193820426 @default.
- W2073442331 hasConcept C2777542201 @default.
- W2073442331 hasConcept C30481170 @default.
- W2073442331 hasConcept C53226629 @default.
- W2073442331 hasConcept C54355233 @default.
- W2073442331 hasConcept C7602840 @default.
- W2073442331 hasConcept C84597430 @default.
- W2073442331 hasConcept C86803240 @default.