Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073447947> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2073447947 endingPage "59" @default.
- W2073447947 startingPage "55" @default.
- W2073447947 abstract "Essential differences are demonstrated between bilirubin binding to rat serum proteins and to albumin in human serum. Acidimetric titration of rat serum with and without added bilirubin shows that binding of bilirubin acid in the range of pH from 6.8 to 8.8 takes place with release of less than one hydrogen ion per molecule of bound bilirubin. With human serum, two hydrogen ions are released, indicating binding of bilirubin dianion. The binding equilibrium of N-[4-[(4-aminophenyl)-sulfonyl]phenyl]-acetamide (MADDS) to rat serum albumin is influenced slightly by cobinding of bilirubin whereas MADDS and bilirubin bind competitively to human serum albumin. Finally, the rate of oxidation of bilirubin with hydrogen peroxide and peroxidase is decreased moderately by addition of rat serum albumin and strongly by the human protein, indicating that biliribin in its complex with rat serum albumin is subject to oxidation while the complex with human serum albumin is protected. These differences should be considered when rats are used as a model in experimental studies aiming at prevention of bilirubin encephalopathy in human neonates." @default.
- W2073447947 created "2016-06-24" @default.
- W2073447947 creator A5005904195 @default.
- W2073447947 creator A5026760088 @default.
- W2073447947 date "1986-01-01" @default.
- W2073447947 modified "2023-09-23" @default.
- W2073447947 title "Bilirubin/Rat Serum Albumin Interaction." @default.
- W2073447947 doi "https://doi.org/10.3891/acta.chem.scand.40b-0055" @default.
- W2073447947 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3962551" @default.
- W2073447947 hasPublicationYear "1986" @default.
- W2073447947 type Work @default.
- W2073447947 sameAs 2073447947 @default.
- W2073447947 citedByCount "13" @default.
- W2073447947 countsByYear W20734479472017 @default.
- W2073447947 countsByYear W20734479472019 @default.
- W2073447947 countsByYear W20734479472020 @default.
- W2073447947 crossrefType "journal-article" @default.
- W2073447947 hasAuthorship W2073447947A5005904195 @default.
- W2073447947 hasAuthorship W2073447947A5026760088 @default.
- W2073447947 hasBestOaLocation W20734479471 @default.
- W2073447947 hasConcept C134018914 @default.
- W2073447947 hasConcept C165616093 @default.
- W2073447947 hasConcept C185592680 @default.
- W2073447947 hasConcept C2776125364 @default.
- W2073447947 hasConcept C2777513400 @default.
- W2073447947 hasConcept C2778597219 @default.
- W2073447947 hasConcept C55493867 @default.
- W2073447947 hasConcept C86803240 @default.
- W2073447947 hasConcept C86807702 @default.
- W2073447947 hasConceptScore W2073447947C134018914 @default.
- W2073447947 hasConceptScore W2073447947C165616093 @default.
- W2073447947 hasConceptScore W2073447947C185592680 @default.
- W2073447947 hasConceptScore W2073447947C2776125364 @default.
- W2073447947 hasConceptScore W2073447947C2777513400 @default.
- W2073447947 hasConceptScore W2073447947C2778597219 @default.
- W2073447947 hasConceptScore W2073447947C55493867 @default.
- W2073447947 hasConceptScore W2073447947C86803240 @default.
- W2073447947 hasConceptScore W2073447947C86807702 @default.
- W2073447947 hasLocation W20734479471 @default.
- W2073447947 hasLocation W20734479472 @default.
- W2073447947 hasOpenAccess W2073447947 @default.
- W2073447947 hasPrimaryLocation W20734479471 @default.
- W2073447947 hasRelatedWork W1749195494 @default.
- W2073447947 hasRelatedWork W1990174089 @default.
- W2073447947 hasRelatedWork W1992957793 @default.
- W2073447947 hasRelatedWork W2053583917 @default.
- W2073447947 hasRelatedWork W2073447947 @default.
- W2073447947 hasRelatedWork W2076179785 @default.
- W2073447947 hasRelatedWork W2415885697 @default.
- W2073447947 hasRelatedWork W4247786410 @default.
- W2073447947 hasRelatedWork W68401319 @default.
- W2073447947 hasRelatedWork W2002771946 @default.
- W2073447947 hasVolume "40b" @default.
- W2073447947 isParatext "false" @default.
- W2073447947 isRetracted "false" @default.
- W2073447947 magId "2073447947" @default.
- W2073447947 workType "article" @default.