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• W2073451154 abstract "Preimplantation embryos of many species are known to synthesize prostaglandins. These tissue hormones are believed to influence embryonic metabolism, as well as embryo-maternal interaction during implantation although their putative role(s) remains obscure. Here, prostaglandin production by blastocysts from cynomolgus monkeys (Macaca fascicularis) was examined qualitatively during in vitro culture. Tritium labelled arachidonic acid was metabolized to 6 keto-prostaglandin F1α, 2, 3-dinor-prostaglandin F1α and thromboxane B2 as characterized by HLPC separation. Also, 6-keto-prostaglandin F1α and thromboxane B2 were identified by specific RIA's. Our data suggest that the main arachidonic acid metabolites produced by blastocysts of cynomolgus monkeys are prostacyclin and thromboxane." @default.
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• W2073451154 date "1991-08-01" @default.
• W2073451154 modified "2023-09-26" @default.
• W2073451154 title "Arachidonic acid metabolism and prostaglandin production by primate preimplantation blastocysts" @default.
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• W2073451154 doi "https://doi.org/10.1016/0090-6980(91)90071-m" @default.
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