Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073462893> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2073462893 endingPage "341" @default.
- W2073462893 startingPage "337" @default.
- W2073462893 abstract "Malignant transformation of cells is frequently associated with abnormalities in HLA expression. These abnormalities may play a significant role in the clinical course of the disease because the cellular immune response to tumors relies on concomitant recognition of tumor antigens with self-HLA molecules. Since HLA molecules mediate interactions of tumor cells with specific receptors on T and natural killer (NK) cells, tight control of expression of HLA molecules is critical for initiation and implementation of an effective cellular immune response. There is not much information on HLA class I antigens in conjunctival carcinomas. We studied the immunoexpression of HLA class I antigen and beta2-microglobulin (beta2-m) in conjunctival dysplasias and conjunctival squamous cell carcinomas.HLA class I antigen and beta2-m expression were analyzed in 10 conjunctival dysplasias, 6 carcinomas in situ, and in 11 conjunctival carcinomas by immunoperoxidase staining with monoclonal antibodies to HLA class I antigen and beta2-m on the archival clinical samples. Immunoanalysis was done according to the International Histocompatibility Working Group Project Description.HLA class I antigen and beta2-m were heterogeneous in 10 conjunctival dysplasias, negative in 6 carcinomas in situ, and 11 conjunctival squamous cell carcinomas. The difference of immunoexpression for HLA class I and beta2-m among the 3 groups was statistically significant (P <0.001).HLA class I antigens and beta2-m are decreased in conjunctival dysplasias and negative in carcinomas in situ, and carcinomas. The findings support the role of cytotoxic T lymphocyte-mediated control of tumor growth in the clinical course of conjunctival squamous cell carcinomas." @default.
- W2073462893 created "2016-06-24" @default.
- W2073462893 creator A5010148762 @default.
- W2073462893 creator A5023761882 @default.
- W2073462893 creator A5024833564 @default.
- W2073462893 creator A5043835740 @default.
- W2073462893 creator A5049947470 @default.
- W2073462893 creator A5072272304 @default.
- W2073462893 date "2005-04-01" @default.
- W2073462893 modified "2023-09-24" @default.
- W2073462893 title "Human Leukocyte Class I Antigen and ??2-Microglobulin Expression in Conjunctival Dysplasia, Carcinoma In Situ, and Squamous Cell Carcinoma" @default.
- W2073462893 cites W1980621729 @default.
- W2073462893 cites W1997959183 @default.
- W2073462893 cites W2002703904 @default.
- W2073462893 cites W2028065627 @default.
- W2073462893 cites W2052456668 @default.
- W2073462893 cites W2059378562 @default.
- W2073462893 cites W2063366670 @default.
- W2073462893 cites W2073673847 @default.
- W2073462893 cites W2104935974 @default.
- W2073462893 cites W2111441225 @default.
- W2073462893 cites W2132032857 @default.
- W2073462893 cites W2171986697 @default.
- W2073462893 cites W4236920401 @default.
- W2073462893 cites W4322387795 @default.
- W2073462893 doi "https://doi.org/10.1097/01.ico.0000141238.71837.3c" @default.
- W2073462893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15778609" @default.
- W2073462893 hasPublicationYear "2005" @default.
- W2073462893 type Work @default.
- W2073462893 sameAs 2073462893 @default.
- W2073462893 citedByCount "2" @default.
- W2073462893 countsByYear W20734628932016 @default.
- W2073462893 crossrefType "journal-article" @default.
- W2073462893 hasAuthorship W2073462893A5010148762 @default.
- W2073462893 hasAuthorship W2073462893A5023761882 @default.
- W2073462893 hasAuthorship W2073462893A5024833564 @default.
- W2073462893 hasAuthorship W2073462893A5043835740 @default.
- W2073462893 hasAuthorship W2073462893A5049947470 @default.
- W2073462893 hasAuthorship W2073462893A5072272304 @default.
- W2073462893 hasConcept C142724271 @default.
- W2073462893 hasConcept C147483822 @default.
- W2073462893 hasConcept C154317977 @default.
- W2073462893 hasConcept C159654299 @default.
- W2073462893 hasConcept C188280979 @default.
- W2073462893 hasConcept C202751555 @default.
- W2073462893 hasConcept C203014093 @default.
- W2073462893 hasConcept C207936829 @default.
- W2073462893 hasConcept C21957315 @default.
- W2073462893 hasConcept C2775894508 @default.
- W2073462893 hasConcept C2777546739 @default.
- W2073462893 hasConcept C2777661416 @default.
- W2073462893 hasConcept C542903549 @default.
- W2073462893 hasConcept C55493867 @default.
- W2073462893 hasConcept C71924100 @default.
- W2073462893 hasConcept C86803240 @default.
- W2073462893 hasConceptScore W2073462893C142724271 @default.
- W2073462893 hasConceptScore W2073462893C147483822 @default.
- W2073462893 hasConceptScore W2073462893C154317977 @default.
- W2073462893 hasConceptScore W2073462893C159654299 @default.
- W2073462893 hasConceptScore W2073462893C188280979 @default.
- W2073462893 hasConceptScore W2073462893C202751555 @default.
- W2073462893 hasConceptScore W2073462893C203014093 @default.
- W2073462893 hasConceptScore W2073462893C207936829 @default.
- W2073462893 hasConceptScore W2073462893C21957315 @default.
- W2073462893 hasConceptScore W2073462893C2775894508 @default.
- W2073462893 hasConceptScore W2073462893C2777546739 @default.
- W2073462893 hasConceptScore W2073462893C2777661416 @default.
- W2073462893 hasConceptScore W2073462893C542903549 @default.
- W2073462893 hasConceptScore W2073462893C55493867 @default.
- W2073462893 hasConceptScore W2073462893C71924100 @default.
- W2073462893 hasConceptScore W2073462893C86803240 @default.
- W2073462893 hasIssue "3" @default.
- W2073462893 hasLocation W20734628931 @default.
- W2073462893 hasLocation W20734628932 @default.
- W2073462893 hasOpenAccess W2073462893 @default.
- W2073462893 hasPrimaryLocation W20734628931 @default.
- W2073462893 hasRelatedWork W1492046881 @default.
- W2073462893 hasRelatedWork W1986070284 @default.
- W2073462893 hasRelatedWork W1990222908 @default.
- W2073462893 hasRelatedWork W2006911370 @default.
- W2073462893 hasRelatedWork W2008949385 @default.
- W2073462893 hasRelatedWork W2053177727 @default.
- W2073462893 hasRelatedWork W2060941543 @default.
- W2073462893 hasRelatedWork W2086554538 @default.
- W2073462893 hasRelatedWork W208718216 @default.
- W2073462893 hasRelatedWork W2474575137 @default.
- W2073462893 hasVolume "24" @default.
- W2073462893 isParatext "false" @default.
- W2073462893 isRetracted "false" @default.
- W2073462893 magId "2073462893" @default.
- W2073462893 workType "article" @default.