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• W2073473739 abstract "To determine the relationship between parental major depression and respiratory illness in youth.Three-generation family cohort study.Baseline study initiated at the Yale University Depression Research Unit.One hundred sixty-one children and their parents and grandparents.Family history of major depression.We studied the lifetime prevalence of respiratory illness and a range of other physical disorders, including gastrointestinal, neurodevelopmental, and cardiovascular diseases, in offspring of parents with and without major depression. Analyses were also stratified by parental and grandparental major depression status and were adjusted for age, sex, parental prenatal smoking, and parental functional impairment.Parental major depression is associated with a significantly increased likelihood of respiratory illness in youth (odds ratio, 3.7; 95% confidence interval, 1.6-8.6). This association persists after adjusting for age, sex, parental prenatal smoking, parental respiratory disease, and parental functional impairment.Our results suggest that youth of parents with major depression may have heightened vulnerability to respiratory illness. Neither parental respiratory illness, prenatal smoking, nor functional impairment appears to explain this link." @default.
• W2073473739 created "2016-06-24" @default.
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• W2073473739 date "2007-05-01" @default.
• W2073473739 modified "2023-09-27" @default.
• W2073473739 title "Familial Depression and Respiratory Illness in Children" @default.
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• W2073473739 doi "https://doi.org/10.1001/archpedi.161.5.487" @default.
• W2073473739 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17485626" @default.
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