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- W2073474377 abstract "It is hypothesized that the presence of psychotic features may define a subtype of bipolar disorder that is more homogeneous in its genetic predisposition than bipolar disorder as a whole. We used psychosis as an alternative phenotype definition in a re-analysis of the NIMH Bipolar Genetics Initiative data sets. In this analysis we selected only those families in which at least two members were diagnosed with bipolar disorder type 1 with psychotic features. This analysis identified a linkage signal on chromosome 5q33-q34, a region previously implicated in independent linkage studies of schizophrenia and of psychosis, broadly defined. This finding is consistent with the hypothesis that susceptibility to psychosis may characterize at least a subtype of bipolar disorder. © 2006 Wiley-Liss, Inc." @default.
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- W2073474377 date "2006-01-01" @default.
- W2073474377 modified "2023-10-16" @default.
- W2073474377 title "Evidence of linkage to psychosis on chromosome 5q33-34 in pedigrees ascertained for bipolar disorder" @default.
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- W2073474377 doi "https://doi.org/10.1002/ajmg.b.30402" @default.
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