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- W2073506558 abstract "Indiplon is a short-acting hypnotic that is currently being developed as a treatment for insomnia by Neurocrine Biosciences and Pfizer, and is expected to be marketed in mid-2006. It is a high-affinity allosteric potentiator of GABAA responses that demonstrates preference for alpha1 subunit-containing GABAA receptors. Indiplon will be an addition to the general category of newer-generation hypnotics that now includes zaleplon, zolpidem, zopiclone and eszopiclone. Clinical trials were carried out with an immediate-release capsule and a modified-release tablet and demonstrate very positive efficacy and safety profiles. The major challenge will be developing a commercial success in the crowded insomnia treatment marketplace." @default.
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- W2073506558 date "2005-09-27" @default.
- W2073506558 modified "2023-10-16" @default.
- W2073506558 title "Indiplon: the development of a new hypnotic" @default.
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- W2073506558 doi "https://doi.org/10.1517/13543784.14.10.1269" @default.
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