FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073519165> ?p ?o ?g. }

• W2073519165 endingPage "323" @default.
• W2073519165 startingPage "317" @default.
• W2073519165 abstract "The isoflavone genistein (Gen) is a naturally occurring phytoestrogen found in high concentrations in soy. The biological effects of Gen have been extensively studied. The immunomodulating properties of Gen are, however, less well investigated and the results are contradictory. Our aim was to study possible estrogen agonistic and antagonistic properties of Gen in uterus, bone, lymphopoiesis and B‐cell function by comparing effects in castrated and intact female mice, respectively. Oophorectomized (OVX) and sham‐operated mice were treated with s.c. doses of 17β‐estradiol (E2) (0.16 mg/kg), Gen (50 mg/kg), or vehicle (olive oil) as control. Effects on bone mineral density (BMD) were studied using peripheral quantitative computerized tomography, uterine and thymus weights were examined, lymphopoiesis in thymus and bone marrow was analyzed using flow cytometry, and the frequency of immunoglobulin‐producing B cells in bone marrow and spleen was studied using an ELISPOT assay. Gen was clearly antagonizing endogenous estrogen in sham‐operated female mice as shown by inhibiting the uterine weight and by increasing the frequency of B lymphopoietic cells in bone marrow. The only agonistic effect of Gen was shown by increased BMD in OVX mice. Our results are discussed in the context of estrogen receptor biology." @default.
• W2073519165 created "2016-06-24" @default.
• W2073519165 creator A5075679467 @default.
• W2073519165 creator A5081675693 @default.
• W2073519165 creator A5087766994 @default.
• W2073519165 creator A5088403071 @default.
• W2073519165 creator A5091032474 @default.
• W2073519165 date "2005-05-01" @default.
• W2073519165 modified "2023-10-16" @default.
• W2073519165 title "Estrogenic agonism and antagonism of the soy isoflavone genistein in uterus, bone and lymphopoiesis in mice" @default.
• W2073519165 cites W1481844387 @default.
• W2073519165 cites W1498384054 @default.
• W2073519165 cites W1518129172 @default.
• W2073519165 cites W1590467919 @default.
• W2073519165 cites W1655746649 @default.
• W2073519165 cites W1908178761 @default.
• W2073519165 cites W1965764974 @default.
• W2073519165 cites W1966088006 @default.
• W2073519165 cites W1995946399 @default.
• W2073519165 cites W2009230922 @default.
• W2073519165 cites W2011949041 @default.
• W2073519165 cites W2021427813 @default.
• W2073519165 cites W2021485462 @default.
• W2073519165 cites W2026836636 @default.
• W2073519165 cites W2027259461 @default.
• W2073519165 cites W2034359758 @default.
• W2073519165 cites W2034938926 @default.
• W2073519165 cites W2045590883 @default.
• W2073519165 cites W2063947339 @default.
• W2073519165 cites W2065563651 @default.
• W2073519165 cites W2072308232 @default.
• W2073519165 cites W2075654456 @default.
• W2073519165 cites W2085120242 @default.
• W2073519165 cites W2098359902 @default.
• W2073519165 cites W2120758873 @default.
• W2073519165 cites W2128727471 @default.
• W2073519165 cites W2130076367 @default.
• W2073519165 cites W2135299810 @default.
• W2073519165 cites W2136672074 @default.
• W2073519165 cites W2139009678 @default.
• W2073519165 cites W2146975650 @default.
• W2073519165 cites W2159361509 @default.
• W2073519165 cites W3169342595 @default.
• W2073519165 cites W4255980522 @default.
• W2073519165 doi "https://doi.org/10.1111/j.1600-0463.2005.apm_113502.x" @default.
• W2073519165 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16011657" @default.
• W2073519165 hasPublicationYear "2005" @default.
• W2073519165 type Work @default.
• W2073519165 sameAs 2073519165 @default.
• W2073519165 citedByCount "33" @default.
• W2073519165 countsByYear W20735191652012 @default.
• W2073519165 countsByYear W20735191652014 @default.
• W2073519165 countsByYear W20735191652015 @default.
• W2073519165 countsByYear W20735191652016 @default.
• W2073519165 countsByYear W20735191652017 @default.
• W2073519165 countsByYear W20735191652018 @default.
• W2073519165 countsByYear W20735191652019 @default.
• W2073519165 countsByYear W20735191652023 @default.
• W2073519165 crossrefType "journal-article" @default.
• W2073519165 hasAuthorship W2073519165A5075679467 @default.
• W2073519165 hasAuthorship W2073519165A5081675693 @default.
• W2073519165 hasAuthorship W2073519165A5087766994 @default.
• W2073519165 hasAuthorship W2073519165A5088403071 @default.
• W2073519165 hasAuthorship W2073519165A5091032474 @default.
• W2073519165 hasConcept C109159458 @default.
• W2073519165 hasConcept C121608353 @default.
• W2073519165 hasConcept C126322002 @default.
• W2073519165 hasConcept C134018914 @default.
• W2073519165 hasConcept C185592680 @default.
• W2073519165 hasConcept C2776541429 @default.
• W2073519165 hasConcept C2776886416 @default.
• W2073519165 hasConcept C2777164284 @default.
• W2073519165 hasConcept C2778298627 @default.
• W2073519165 hasConcept C2780007613 @default.
• W2073519165 hasConcept C28328180 @default.
• W2073519165 hasConcept C530470458 @default.
• W2073519165 hasConcept C54355233 @default.
• W2073519165 hasConcept C71924100 @default.
• W2073519165 hasConcept C79904392 @default.
• W2073519165 hasConcept C84606932 @default.
• W2073519165 hasConcept C86803240 @default.
• W2073519165 hasConceptScore W2073519165C109159458 @default.
• W2073519165 hasConceptScore W2073519165C121608353 @default.
• W2073519165 hasConceptScore W2073519165C126322002 @default.
• W2073519165 hasConceptScore W2073519165C134018914 @default.
• W2073519165 hasConceptScore W2073519165C185592680 @default.
• W2073519165 hasConceptScore W2073519165C2776541429 @default.
• W2073519165 hasConceptScore W2073519165C2776886416 @default.
• W2073519165 hasConceptScore W2073519165C2777164284 @default.
• W2073519165 hasConceptScore W2073519165C2778298627 @default.
• W2073519165 hasConceptScore W2073519165C2780007613 @default.
• W2073519165 hasConceptScore W2073519165C28328180 @default.
• W2073519165 hasConceptScore W2073519165C530470458 @default.
• W2073519165 hasConceptScore W2073519165C54355233 @default.
• W2073519165 hasConceptScore W2073519165C71924100 @default.
• W2073519165 hasConceptScore W2073519165C79904392 @default.
• W2073519165 hasConceptScore W2073519165C84606932 @default.
• W2073519165 hasConceptScore W2073519165C86803240 @default.

• next