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• W2073598357 abstract "Insomnia is a hugely prevalent problem, affecting between 7% and 20% of the adult population depending on criteria used, and increasing in prevalence with age. It causes significant impairment in quality of life (see Alford and Wilson, 2008), and the degree of impairment correlates with severity of sleep disturbance and affects employment, physical and social role functioning, and mental health. Sufferers report fatigue, diminished energy and concentration, and memory disturbance. Economic implications include not only the direct costs of diagnosis and treatment (including prescription and non-prescription drugs and self-medication with alcohol) but also costs related to absenteeism, reduced productivity, accidents and increased GP visits that are secondary to the insomnia (Godet-Cayre, et al., 2006; Leger, 1994; Chevalier, et al., 1999). Insomnia is a long-term problem, with many patients reporting duration of more than 20 years (Green, et al., 2005). There is growing evidence from epidemiological studies that insomnia increases the risk of future disorders such as anxiety and depression. The National Institute of Mental Health Epidemiologic Catchment Area study 20 years ago interviewed 7954 adults on two occasions a year apart and found that 14% of those who had insomnia at the first interview had developed new major depression a year later (Ford and Kamerow, 1989). This data has been augmented by several more recent reports of increased risk. A survey of 1200 young adults in Michigan found that the odds ratio of new depression was four times increased in those subjects who had insomnia 3 years earlier (Breslau, et al., 1996) and in a longitudinal population study in Norway those with insomnia were at increased risk of anxiety disorders at the second contact 10 years later (Neckelmann, et al., 2007). As well as being a risk factor for mental illness insomnia is also very prevalent in psychiatric populations with up to 90% of depressed patients having this symptom (Stewart, et al., 2006). It is usually long-lasting – often predating the onset of the psychiatric disorder and if not fully treated is often a risk factor for relapse (Dombrovski, et al., 2007)." @default.
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• W2073598357 date "2008-09-01" @default.
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• W2073598357 title "Drug treatment of chronic insomnia — dawn at the end of a long night?" @default.
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