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- W2073607380 abstract "<b>Background</b> Stage IA of non–small cell lung cancer (NSCLC) is divided into two subgroups, T1aN0M0 (<i>d</i> ≤ 2 cm) and T1bN0M0 (2 < <i>d</i> ≤ 3 cm), in the International Association for the Study of Lung Cancer, seventh edition of <i>TNM Classification of Malignant Tumors</i>. <b>Objective</b> The purpose of this study was the identification of independent clinicopathological predictors of prognosis of these two subgroups of NSCLC. <b>Methods</b> Between 1986 and 2005, a cohort of 1,929 cases of stage IA NSCLC in Tian Jin Medical University Cancer Institute and Hospital were retrospectively analyzed. The impact of clinicopathological characteristics on patients' survival was investigated. <b>Results</b> The overall 5-year survival rate was 71.07%. Patients with T1aN0M0 NSCLC had a better 5-year survival than those with T1bN0M0 (73.98 vs. 68.18%, <i>p</i> = 0.0135). The Cox proportional hazard model revealed that the prognostic factors of T1aN0M0 were intratumoral vessel invasion (<i>p</i> = 0.035) and histologic differentiation (<i>p</i> = 0.004). In patients with T1bN0M0 NSCLC, the prognostic factors were histologic differentiation (<i>p</i> < 0.01), intratumoral vessel invasion (<i>p</i> < 0.01), removal of 6 or more lymph node stations (<i>p</i> < 0.01), and removal of lymph node station 7 (<i>p</i> < 0.01). <b>Conclusion</b> Prognostic factors of T1aN0M0 and T1bN0M0 NSCLC are different. In patients with T1bN0M0 NSCLC, 6 or more lymph node stations and lymph node station 7 should be removed." @default.
- W2073607380 created "2016-06-24" @default.
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- W2073607380 date "2012-12-06" @default.
- W2073607380 modified "2023-09-23" @default.
- W2073607380 title "T1aN0M0 and T1bN0M0 Non–Small Cell Lung Cancer: A Retrospective Study of the Prognosis" @default.
- W2073607380 doi "https://doi.org/10.1055/s-0032-1329191" @default.
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