Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073608963> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2073608963 endingPage "576" @default.
- W2073608963 startingPage "576" @default.
- W2073608963 abstract "The common ALL antigen (CALLA) is a unique cell surface glycoprotein detected on the lymphoblasts of most cases of childhood ALL and some B cell tumors to which Ritz et al (Nature 283: 583, 1980) have generated a cytolytic monoclonal antibody (J-5). To determine whether J-5 is distributed on the surfaces of hematopoietic progenitors and with the ultimate purpose of developing a useful approach to autotransplantation, we thrice exposed normal marrow and blood mononuclear cells to J-5 and complement after having determined that such treatment is sufficient to eradicate >99% J-5+ lymphoblasts. The cells were then cultured in both plasma clot and methylcellulose systems to which were added appropriate inducers. Erythroid, granuloid and mixed erythroid/granuloid colony growth was unaffected both with respect to number, size, and morphology. The normal colonies were preserved even in experiments in which J-5+ leukemic cells were added to the normal marrows and lysed during antibody exposure. These results suggest that CALLA is absent from the surface of committed marrow and peripheral blood myeloid progenitors. The antibody is a powerful potential tool for elimination of CALLA+ lymphoblasts from marrow prior to autologous bone marrow transplantation." @default.
- W2073608963 created "2016-06-24" @default.
- W2073608963 creator A5007271347 @default.
- W2073608963 creator A5008718116 @default.
- W2073608963 creator A5024304426 @default.
- W2073608963 creator A5031553531 @default.
- W2073608963 creator A5044759942 @default.
- W2073608963 creator A5082614208 @default.
- W2073608963 creator A5091766856 @default.
- W2073608963 date "1981-04-01" @default.
- W2073608963 modified "2023-09-26" @default.
- W2073608963 title "801 ABSENCE OF COMMON ALL ANTIGEN ON NORMAL PLURIPOTENTIAL MYELOID, ERYTHROID AND GRANULOCYTE PROGENITORS" @default.
- W2073608963 doi "https://doi.org/10.1203/00006450-198104001-00825" @default.
- W2073608963 hasPublicationYear "1981" @default.
- W2073608963 type Work @default.
- W2073608963 sameAs 2073608963 @default.
- W2073608963 citedByCount "0" @default.
- W2073608963 crossrefType "journal-article" @default.
- W2073608963 hasAuthorship W2073608963A5007271347 @default.
- W2073608963 hasAuthorship W2073608963A5008718116 @default.
- W2073608963 hasAuthorship W2073608963A5024304426 @default.
- W2073608963 hasAuthorship W2073608963A5031553531 @default.
- W2073608963 hasAuthorship W2073608963A5044759942 @default.
- W2073608963 hasAuthorship W2073608963A5082614208 @default.
- W2073608963 hasAuthorship W2073608963A5091766856 @default.
- W2073608963 hasBestOaLocation W20736089631 @default.
- W2073608963 hasConcept C109159458 @default.
- W2073608963 hasConcept C113842279 @default.
- W2073608963 hasConcept C137061746 @default.
- W2073608963 hasConcept C147483822 @default.
- W2073608963 hasConcept C153911025 @default.
- W2073608963 hasConcept C159654299 @default.
- W2073608963 hasConcept C201750760 @default.
- W2073608963 hasConcept C202751555 @default.
- W2073608963 hasConcept C203014093 @default.
- W2073608963 hasConcept C2777820912 @default.
- W2073608963 hasConcept C2779282312 @default.
- W2073608963 hasConcept C2780007613 @default.
- W2073608963 hasConcept C28328180 @default.
- W2073608963 hasConcept C542903549 @default.
- W2073608963 hasConcept C54355233 @default.
- W2073608963 hasConcept C55493867 @default.
- W2073608963 hasConcept C81885089 @default.
- W2073608963 hasConcept C86803240 @default.
- W2073608963 hasConcept C95444343 @default.
- W2073608963 hasConceptScore W2073608963C109159458 @default.
- W2073608963 hasConceptScore W2073608963C113842279 @default.
- W2073608963 hasConceptScore W2073608963C137061746 @default.
- W2073608963 hasConceptScore W2073608963C147483822 @default.
- W2073608963 hasConceptScore W2073608963C153911025 @default.
- W2073608963 hasConceptScore W2073608963C159654299 @default.
- W2073608963 hasConceptScore W2073608963C201750760 @default.
- W2073608963 hasConceptScore W2073608963C202751555 @default.
- W2073608963 hasConceptScore W2073608963C203014093 @default.
- W2073608963 hasConceptScore W2073608963C2777820912 @default.
- W2073608963 hasConceptScore W2073608963C2779282312 @default.
- W2073608963 hasConceptScore W2073608963C2780007613 @default.
- W2073608963 hasConceptScore W2073608963C28328180 @default.
- W2073608963 hasConceptScore W2073608963C542903549 @default.
- W2073608963 hasConceptScore W2073608963C54355233 @default.
- W2073608963 hasConceptScore W2073608963C55493867 @default.
- W2073608963 hasConceptScore W2073608963C81885089 @default.
- W2073608963 hasConceptScore W2073608963C86803240 @default.
- W2073608963 hasConceptScore W2073608963C95444343 @default.
- W2073608963 hasLocation W20736089631 @default.
- W2073608963 hasOpenAccess W2073608963 @default.
- W2073608963 hasPrimaryLocation W20736089631 @default.
- W2073608963 hasRelatedWork W1973692620 @default.
- W2073608963 hasRelatedWork W1977841877 @default.
- W2073608963 hasRelatedWork W2025279110 @default.
- W2073608963 hasRelatedWork W2066354959 @default.
- W2073608963 hasRelatedWork W2170097602 @default.
- W2073608963 hasRelatedWork W2282986807 @default.
- W2073608963 hasRelatedWork W2285393345 @default.
- W2073608963 hasRelatedWork W2405181172 @default.
- W2073608963 hasRelatedWork W2438891372 @default.
- W2073608963 hasRelatedWork W4313381867 @default.
- W2073608963 hasVolume "15" @default.
- W2073608963 isParatext "false" @default.
- W2073608963 isRetracted "false" @default.
- W2073608963 magId "2073608963" @default.
- W2073608963 workType "article" @default.