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• W2073617532 abstract "We report a dog with dystrophic epidermolysis bullosa. This 4‐year‐old female Akita Inu, a species of Canis familiaris var. japanicus Temminck, had a 3‐year‐history of ulcers and scars over the pressure areas on the limbs, and dystrophic nails, since the age of 1 year, which corresponds lo early adulthood in humans. Electron microscopy of a blister revealed separation beneath the lamina densa, and a reduction in the number of anchoring fibrils. The NC‐1 domain of type VII collagen was positively stained with monoclonal anlibody LH7.2 at the basement membrane zone. These findings indicate that humans and dogs have a similar response to antibody LH7.2, which may aid the development of an animal model for this disease." @default.
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• W2073617532 date "1995-12-01" @default.
• W2073617532 modified "2023-10-11" @default.
• W2073617532 title "Dystrophic form of inherited epidermolysis bullosa in a dog (Akita Inu)" @default.
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• W2073617532 doi "https://doi.org/10.1111/j.1365-2133.1995.tb06942.x" @default.
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