Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073629069> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2073629069 abstract "Several molecules are known to be involved in T-cell activation via the TCR/CD3 complex and while the mechanisms of late T cell signaling have been well characterized, the very early events are still not fully understood.The aim of this study was to identify yet unknown molecules associated with the TCR/CD3 complex.To identify new molecules associated with the TCR/CD3 complex, a monoclonal antibody termed MT3 was produced by immunoprecipitated beads immunization. Colocalization of the MT3 mAb recognizing molecules with the TCR/CD3 complexes was verified by confocal microscopic analysis. The surface antigen recognized by MT3 antibody was expressed on a subpopulation of CD3+ T cells, and on both CD4+ and CD8+ lymphocytes. The antigen was also expressed on na?ve CD4+ T cells and on a subset of memory CD4+ T cells. In contrast, in the CD8 population, the majority of MT3+ cells were found in the na?ve population. The MT3 mAb recognizing molecules were also expressed on red blood cells but only in particular subjects. Similar to peripheral blood leukocytes, MT3 mAb recognizing molecules are exclusively expressed on T cell lines.Based on the cellular distribution patterns and confocal microscopic analysis, the MT3 mAb recognizing molecule that we investigated is proposed to be a TCR/CD3 associated molecule and might be involved in the antigen recognition of T cells." @default.
- W2073629069 created "2016-06-24" @default.
- W2073629069 creator A5003915697 @default.
- W2073629069 creator A5005293594 @default.
- W2073629069 creator A5039459577 @default.
- W2073629069 creator A5071377696 @default.
- W2073629069 date "2015-03-01" @default.
- W2073629069 modified "2023-09-26" @default.
- W2073629069 title "Identification of a T cell surface molecule using a monoclonal antibody produced by TCR/CD3 complex immunization" @default.
- W2073629069 cites W1973408602 @default.
- W2073629069 cites W1978721703 @default.
- W2073629069 cites W1987295549 @default.
- W2073629069 cites W1995160780 @default.
- W2073629069 cites W2014307955 @default.
- W2073629069 cites W2022642838 @default.
- W2073629069 cites W2022771514 @default.
- W2073629069 cites W2025748968 @default.
- W2073629069 cites W2029720028 @default.
- W2073629069 cites W2030522563 @default.
- W2073629069 cites W2042221539 @default.
- W2073629069 cites W2056207883 @default.
- W2073629069 cites W2071072817 @default.
- W2073629069 cites W2082949819 @default.
- W2073629069 cites W2084388859 @default.
- W2073629069 cites W2091328252 @default.
- W2073629069 cites W2096234619 @default.
- W2073629069 cites W2100412095 @default.
- W2073629069 cites W2116364705 @default.
- W2073629069 cites W2124983348 @default.
- W2073629069 cites W2127745456 @default.
- W2073629069 cites W2131160889 @default.
- W2073629069 cites W2135935218 @default.
- W2073629069 cites W2148330408 @default.
- W2073629069 doi "https://doi.org/10.12932/ap0538.33.2.2015" @default.
- W2073629069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26141031" @default.
- W2073629069 hasPublicationYear "2015" @default.
- W2073629069 type Work @default.
- W2073629069 sameAs 2073629069 @default.
- W2073629069 citedByCount "1" @default.
- W2073629069 countsByYear W20736290692021 @default.
- W2073629069 crossrefType "journal-article" @default.
- W2073629069 hasAuthorship W2073629069A5003915697 @default.
- W2073629069 hasAuthorship W2073629069A5005293594 @default.
- W2073629069 hasAuthorship W2073629069A5039459577 @default.
- W2073629069 hasAuthorship W2073629069A5071377696 @default.
- W2073629069 hasConcept C114684123 @default.
- W2073629069 hasConcept C147483822 @default.
- W2073629069 hasConcept C153911025 @default.
- W2073629069 hasConcept C159654299 @default.
- W2073629069 hasConcept C167672396 @default.
- W2073629069 hasConcept C19317047 @default.
- W2073629069 hasConcept C203014093 @default.
- W2073629069 hasConcept C2776090121 @default.
- W2073629069 hasConcept C2908647359 @default.
- W2073629069 hasConcept C40209533 @default.
- W2073629069 hasConcept C542903549 @default.
- W2073629069 hasConcept C71924100 @default.
- W2073629069 hasConcept C86803240 @default.
- W2073629069 hasConcept C8891405 @default.
- W2073629069 hasConcept C95444343 @default.
- W2073629069 hasConcept C99454951 @default.
- W2073629069 hasConceptScore W2073629069C114684123 @default.
- W2073629069 hasConceptScore W2073629069C147483822 @default.
- W2073629069 hasConceptScore W2073629069C153911025 @default.
- W2073629069 hasConceptScore W2073629069C159654299 @default.
- W2073629069 hasConceptScore W2073629069C167672396 @default.
- W2073629069 hasConceptScore W2073629069C19317047 @default.
- W2073629069 hasConceptScore W2073629069C203014093 @default.
- W2073629069 hasConceptScore W2073629069C2776090121 @default.
- W2073629069 hasConceptScore W2073629069C2908647359 @default.
- W2073629069 hasConceptScore W2073629069C40209533 @default.
- W2073629069 hasConceptScore W2073629069C542903549 @default.
- W2073629069 hasConceptScore W2073629069C71924100 @default.
- W2073629069 hasConceptScore W2073629069C86803240 @default.
- W2073629069 hasConceptScore W2073629069C8891405 @default.
- W2073629069 hasConceptScore W2073629069C95444343 @default.
- W2073629069 hasConceptScore W2073629069C99454951 @default.
- W2073629069 hasLocation W20736290691 @default.
- W2073629069 hasLocation W20736290692 @default.
- W2073629069 hasOpenAccess W2073629069 @default.
- W2073629069 hasPrimaryLocation W20736290691 @default.
- W2073629069 hasRelatedWork W1486854793 @default.
- W2073629069 hasRelatedWork W1510784682 @default.
- W2073629069 hasRelatedWork W1605454818 @default.
- W2073629069 hasRelatedWork W1964323900 @default.
- W2073629069 hasRelatedWork W1965205011 @default.
- W2073629069 hasRelatedWork W2003301929 @default.
- W2073629069 hasRelatedWork W2130147879 @default.
- W2073629069 hasRelatedWork W2172228770 @default.
- W2073629069 hasRelatedWork W2398758327 @default.
- W2073629069 hasRelatedWork W2413777267 @default.
- W2073629069 isParatext "false" @default.
- W2073629069 isRetracted "false" @default.
- W2073629069 magId "2073629069" @default.
- W2073629069 workType "article" @default.