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• W2073634319 abstract "Terbinafine hydrochloride (TH), a poorly water soluble antifungal agent, was characterized by solid state techniques including differential scanning calorimetry, thermogravimetry, X-ray powder diffraction, optical and electron microscopies, Fourier transform infrared, Raman and solid-state nuclear magnetic resonance spectroscopies and intrinsic dissolution rate (IDR). A colorless single crystal of TH was grown from an ethanol:water solution and its crystalline structure was determined through X-ray single crystal diffraction. Also, a new crystal habit of TH was obtained through the slow solvent evaporation technique revealing a needle-like shape. A comparison between the IDR results for the TH raw material and TH needle-like crystal revealed lower values for the new crystal habit, which can be attributed to the preferential orientation of the crystals in the compressed disks." @default.
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• W2073634319 date "2013-05-01" @default.
• W2073634319 modified "2023-10-16" @default.
• W2073634319 title "Single crystal structure, solid state characterization and dissolution rate of terbinafine hydrochloride" @default.
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• W2073634319 doi "https://doi.org/10.1016/j.jpba.2013.02.001" @default.
• W2073634319 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23474809" @default.
• W2073634319 hasPublicationYear "2013" @default.
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