Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073642206> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2073642206 endingPage "422" @default.
- W2073642206 startingPage "419" @default.
- W2073642206 abstract "<h2>Abstract</h2> It has been proposed that a single preoperative dose of a corticosteroid may protect the myocardium from ischemic injury during open heart surgery. To test this hypothesis, a prospective, randomized, double blind study was carried out in ninety-five patients undergoing coronary bypass surgery using intermittent ischemic arrest with systemic and local hypothermia. Half the patients received 2 gm (approximately 30 mg/kg) of methylprednisolone 2 hours prior to the initiation of cardiopulmonary bypass and the other half received a placebo. Postoperative electrocardiograms and blood levels of serum creatine phosphokinase (CPK), lactic dehydrogenase (LDH), and serum glutamic oxalacetic transaminase (SGOT) were compared in the two groups. No apparent difference was noted in the number of patients with significantly elevated levels of CPK, LDH, or SGOT or in the number with positive isoenzyme patterns of CPK and LDH. Moreover, there was no significant difference in the mean values of CPK, LDH, or SGOT between the two groups. The number of patients with electrocardiographic evidence of myocardial injury (10 per cent) was the same in both groups and no difference was noted in (1) the ease with which patients could be weaned from cardiopulmonary bypass, (2) postoperative arrhythmias, (3) postoperative bleeding, (4) postoperative respiratory insufficiency, and (5) length of hospital stay. It is concluded that a single preoperative dose of 2 gm of methylprednisolone offers no demonstrable protection to the myocardium from the effects of ischemia during coronary artery bypass surgery." @default.
- W2073642206 created "2016-06-24" @default.
- W2073642206 creator A5000114315 @default.
- W2073642206 creator A5001418151 @default.
- W2073642206 creator A5028314457 @default.
- W2073642206 creator A5042444496 @default.
- W2073642206 date "1976-04-01" @default.
- W2073642206 modified "2023-09-26" @default.
- W2073642206 title "Effect of methylprednisolone on myocardial preservation during coronary artery surgery" @default.
- W2073642206 cites W2003495709 @default.
- W2073642206 cites W2034160507 @default.
- W2073642206 cites W2060046372 @default.
- W2073642206 cites W2062185555 @default.
- W2073642206 cites W2096300153 @default.
- W2073642206 cites W2398789870 @default.
- W2073642206 cites W2409601521 @default.
- W2073642206 doi "https://doi.org/10.1016/0002-9610(76)90150-1" @default.
- W2073642206 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/773198" @default.
- W2073642206 hasPublicationYear "1976" @default.
- W2073642206 type Work @default.
- W2073642206 sameAs 2073642206 @default.
- W2073642206 citedByCount "31" @default.
- W2073642206 countsByYear W20736422062014 @default.
- W2073642206 countsByYear W20736422062015 @default.
- W2073642206 countsByYear W20736422062018 @default.
- W2073642206 countsByYear W20736422062022 @default.
- W2073642206 crossrefType "journal-article" @default.
- W2073642206 hasAuthorship W2073642206A5000114315 @default.
- W2073642206 hasAuthorship W2073642206A5001418151 @default.
- W2073642206 hasAuthorship W2073642206A5028314457 @default.
- W2073642206 hasAuthorship W2073642206A5042444496 @default.
- W2073642206 hasConcept C126322002 @default.
- W2073642206 hasConcept C141071460 @default.
- W2073642206 hasConcept C142724271 @default.
- W2073642206 hasConcept C164705383 @default.
- W2073642206 hasConcept C181199279 @default.
- W2073642206 hasConcept C185592680 @default.
- W2073642206 hasConcept C204787440 @default.
- W2073642206 hasConcept C27081682 @default.
- W2073642206 hasConcept C2775901492 @default.
- W2073642206 hasConcept C2776820930 @default.
- W2073642206 hasConcept C2777390192 @default.
- W2073642206 hasConcept C2778881276 @default.
- W2073642206 hasConcept C2780372218 @default.
- W2073642206 hasConcept C2993497327 @default.
- W2073642206 hasConcept C36880943 @default.
- W2073642206 hasConcept C42219234 @default.
- W2073642206 hasConcept C55493867 @default.
- W2073642206 hasConcept C71924100 @default.
- W2073642206 hasConceptScore W2073642206C126322002 @default.
- W2073642206 hasConceptScore W2073642206C141071460 @default.
- W2073642206 hasConceptScore W2073642206C142724271 @default.
- W2073642206 hasConceptScore W2073642206C164705383 @default.
- W2073642206 hasConceptScore W2073642206C181199279 @default.
- W2073642206 hasConceptScore W2073642206C185592680 @default.
- W2073642206 hasConceptScore W2073642206C204787440 @default.
- W2073642206 hasConceptScore W2073642206C27081682 @default.
- W2073642206 hasConceptScore W2073642206C2775901492 @default.
- W2073642206 hasConceptScore W2073642206C2776820930 @default.
- W2073642206 hasConceptScore W2073642206C2777390192 @default.
- W2073642206 hasConceptScore W2073642206C2778881276 @default.
- W2073642206 hasConceptScore W2073642206C2780372218 @default.
- W2073642206 hasConceptScore W2073642206C2993497327 @default.
- W2073642206 hasConceptScore W2073642206C36880943 @default.
- W2073642206 hasConceptScore W2073642206C42219234 @default.
- W2073642206 hasConceptScore W2073642206C55493867 @default.
- W2073642206 hasConceptScore W2073642206C71924100 @default.
- W2073642206 hasIssue "4" @default.
- W2073642206 hasLocation W20736422061 @default.
- W2073642206 hasLocation W20736422062 @default.
- W2073642206 hasOpenAccess W2073642206 @default.
- W2073642206 hasPrimaryLocation W20736422061 @default.
- W2073642206 hasRelatedWork W1971637907 @default.
- W2073642206 hasRelatedWork W2013180207 @default.
- W2073642206 hasRelatedWork W2073642206 @default.
- W2073642206 hasRelatedWork W2118084867 @default.
- W2073642206 hasRelatedWork W2159512267 @default.
- W2073642206 hasRelatedWork W2353091891 @default.
- W2073642206 hasRelatedWork W2364190791 @default.
- W2073642206 hasRelatedWork W2392825975 @default.
- W2073642206 hasRelatedWork W2398789870 @default.
- W2073642206 hasRelatedWork W4282045743 @default.
- W2073642206 hasVolume "131" @default.
- W2073642206 isParatext "false" @default.
- W2073642206 isRetracted "false" @default.
- W2073642206 magId "2073642206" @default.
- W2073642206 workType "article" @default.