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• W2073649446 startingPage "81" @default.
• W2073649446 abstract "Estrogen receptor (ER) ligands can modulate innate and adaptive immunity and hematopoiesis, which may explain the clear sex differences in immune responses during autoimmunity, infection or trauma. Dendritic cells (DC) are antigen presenting cells important for initiation of innate and adaptive immunity, as well as immune tolerance. DC progenitors and terminally differentiated DC express ER, indicating the ER ligands may regulate DC at multiple developmental and functional stages. Although there are profound differences in innate immunity between males and females or upon systemic imposition of sex hormones, studies are just beginning to link these differences to DC. Our and others studies demonstrate that estradiol and other ER ligands regulate the homeostasis of bone marrow myeloid and lymphoid progenitors of DC, as well as DC differentiation mediated by GM-CSF and Flt3 Ligand. Since DC have a brief lifespan, these data suggest that relatively short exposures to ER ligands in vivo will alter DC numbers and intrinsic functional capacity related to their developmental state. Studies in diverse experimental models also show that agonist and antagonist ER ligands modulate DC activation and production of inflammatory mediators. These findings have implications for human health and disease since they suggest that both DC development and functional capacity will be responsive to the physiological, pharmacological and environmental ER ligands to which an individual is exposed in vivo." @default.
• W2073649446 created "2016-06-24" @default.
• W2073649446 creator A5007450045 @default.
• W2073649446 creator A5012051319 @default.
• W2073649446 date "2008-01-01" @default.
• W2073649446 modified "2023-10-16" @default.
• W2073649446 title "Regulation of dendritic cell differentiation and function by estrogen receptor ligands" @default.
• W2073649446 cites W124239641 @default.
• W2073649446 cites W1482479272 @default.
• W2073649446 cites W1487018400 @default.
• W2073649446 cites W1500123828 @default.
• W2073649446 cites W1512208922 @default.
• W2073649446 cites W1512751723 @default.
• W2073649446 cites W1535236030 @default.
• W2073649446 cites W1538293535 @default.
• W2073649446 cites W1543098232 @default.
• W2073649446 cites W1574743126 @default.
• W2073649446 cites W1580310389 @default.
• W2073649446 cites W1590467919 @default.
• W2073649446 cites W1908861496 @default.
• W2073649446 cites W1940713438 @default.
• W2073649446 cites W1968998914 @default.
• W2073649446 cites W1970140452 @default.
• W2073649446 cites W1970514298 @default.
• W2073649446 cites W1970937149 @default.
• W2073649446 cites W1971176443 @default.
• W2073649446 cites W1971993874 @default.
• W2073649446 cites W1972566146 @default.
• W2073649446 cites W1977650430 @default.
• W2073649446 cites W1979667319 @default.
• W2073649446 cites W1982483504 @default.
• W2073649446 cites W1982765235 @default.
• W2073649446 cites W1984340410 @default.
• W2073649446 cites W1986226400 @default.
• W2073649446 cites W1987600595 @default.
• W2073649446 cites W1988391705 @default.
• W2073649446 cites W1990321113 @default.
• W2073649446 cites W1992439632 @default.
• W2073649446 cites W1997708871 @default.
• W2073649446 cites W2006935589 @default.
• W2073649446 cites W2009067699 @default.
• W2073649446 cites W2009365973 @default.
• W2073649446 cites W2009404162 @default.
• W2073649446 cites W2009895172 @default.
• W2073649446 cites W2014088511 @default.
• W2073649446 cites W2022303626 @default.
• W2073649446 cites W2023342349 @default.
• W2073649446 cites W2025773873 @default.
• W2073649446 cites W2027657101 @default.
• W2073649446 cites W2038259804 @default.
• W2073649446 cites W2044767152 @default.
• W2073649446 cites W2048143404 @default.
• W2073649446 cites W2052306492 @default.
• W2073649446 cites W2053583666 @default.
• W2073649446 cites W2054061067 @default.
• W2073649446 cites W2054267961 @default.
• W2073649446 cites W2054581136 @default.
• W2073649446 cites W2056461632 @default.
• W2073649446 cites W2059153388 @default.
• W2073649446 cites W2061974307 @default.
• W2073649446 cites W2063015126 @default.
• W2073649446 cites W2065907531 @default.
• W2073649446 cites W2085151337 @default.
• W2073649446 cites W2085245070 @default.
• W2073649446 cites W2086249405 @default.
• W2073649446 cites W2088783992 @default.
• W2073649446 cites W2093165931 @default.
• W2073649446 cites W2099083931 @default.
• W2073649446 cites W2103748070 @default.
• W2073649446 cites W2114302232 @default.
• W2073649446 cites W2115889659 @default.
• W2073649446 cites W2116245071 @default.
• W2073649446 cites W2117025246 @default.
• W2073649446 cites W2121071871 @default.
• W2073649446 cites W2121454015 @default.
• W2073649446 cites W2123674503 @default.
• W2073649446 cites W2126655919 @default.
• W2073649446 cites W2127546602 @default.
• W2073649446 cites W2133748800 @default.
• W2073649446 cites W2141244265 @default.
• W2073649446 cites W2143333572 @default.
• W2073649446 cites W2153220619 @default.
• W2073649446 cites W2155792963 @default.
• W2073649446 cites W2156831625 @default.
• W2073649446 cites W2156989552 @default.
• W2073649446 cites W2161472648 @default.
• W2073649446 cites W2166676682 @default.
• W2073649446 cites W4238342025 @default.
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• W2073649446 doi "https://doi.org/10.1016/j.cellimm.2007.10.008" @default.
• W2073649446 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2593859" @default.
• W2073649446 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18279845" @default.
• W2073649446 hasPublicationYear "2008" @default.
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