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- W2073727002 abstract "Glucose is unstable in whole blood (1). Fluoride-containing tubes are used to reduce glycolysis, especially when very accurate glucose results are required. Complete inhibition of glycolysis by fluoride can take as long as 4 h, during which time glucose can fall as much as 10 mg/dL (0.6 mmol/L) at room temperature (1), even in samples with normal blood cell counts. This is because fluoride inhibits the enzyme enolase, which acts late in the Embden-Meyerhof pathway, thus allowing the “breakdown” of glucose to intermediate molecules earlier in the glycolytic cycle (2). Is there a better fluoride …" @default.
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- W2073727002 date "2012-12-11" @default.
- W2073727002 modified "2023-09-25" @default.
- W2073727002 title "It’s Time for a Better Blood Collection Tube to Improve the Reliability of Glucose Results" @default.
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- W2073727002 doi "https://doi.org/10.2337/dc12-1312" @default.
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