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- W2073782908 abstract "Adult Fasciola hepatica were placed in fine mesh sacks and implanted into the abdominal cavity of rats. After 3 weeks the main bile ducts from these animals were removed and transverse sections were prepared using standard procedures for light microscopy. The perimeter of the bile duct lumen was then measured and statistically compared to the lumenal perimeter of bile ducts from rats which were implanted with sacks lacking worms. The results indicated that the bile duct perimeter in rats with five or more implanted worms surviving after 3 weeks was nearly twice that of the sham transplants. Futhermore, the histology of the ducts from rats with transplanted worms resembled that observed in rats at 20–40 days after oral infection. Because the sacks prevented physical contact between the worms and the bile duct or liver, these results suggest that the hyperplasia of the biliary tract in fascioliasis is induced by a chemical factor." @default.
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- W2073782908 date "1977-04-01" @default.
- W2073782908 modified "2023-10-17" @default.
- W2073782908 title "Fasciola hepatica: Bile duct enlargement induced in rats after intraperitoneal transplantation" @default.
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- W2073782908 doi "https://doi.org/10.1016/0014-4894(77)90112-6" @default.
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