FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073809314> ?p ?o ?g. }

• W2073809314 endingPage "61" @default.
• W2073809314 startingPage "54" @default.
• W2073809314 abstract "CDX2 is an intestinal transcription factor responsible for regulating the proliferation and differentiation of intestinal epithelial cells. In gastric adenocarcinoma, CDX2 expression is known to be associated with limited invasiveness and intestinal phenotypes. The aims of this study were to analyze CDX2 expression in a series of well-characterized cases of gastric epithelial dysplasia, based on the morphologic and mucin phenotypes, and also to analyze CDX2 expression along the metaplasia-dysplasia-carcinoma sequence. CDX2 expression was evaluated in 69 cases of gastric epithelial dysplasia, 88 cases of intestinal-type early gastric cancers, and 56 cases of advanced gastric cancers. Increased CDX2 expression was more frequently associated with adenomatous-type gastric epithelial dysplasia (27/31, 87%) compared with foveolar (7/15, 47%) or hybrid (10/23, 44%) types of gastric epithelial dysplasia (P=0.001). CDX2 expression correlated with an increase in CD10 expression (P=0.005), and a decrease in MUC5AC expression (P=0.001) in gastric epithelial dysplasia. CDX2 expression was also gradually decreased from gastric epithelial dysplasia, to early and advanced gastric cancers (present in 64, 40 and 27% of the cases, respectively). A negative correlation was also observed between CDX2 expression and the depth of tumor invasion. Our results indicate that CDX2 expression is associated with specific morphological and mucin phenotypes of gastric epithelial dysplasias, and decreases progressively with the advancing stage of gastric cancers, suggesting a possible tumor suppressor role for CDX2." @default.
• W2073809314 created "2016-06-24" @default.
• W2073809314 creator A5001550885 @default.
• W2073809314 creator A5031405252 @default.
• W2073809314 creator A5035763230 @default.
• W2073809314 creator A5038972103 @default.
• W2073809314 creator A5045555694 @default.
• W2073809314 creator A5048031696 @default.
• W2073809314 creator A5059888326 @default.
• W2073809314 creator A5072389805 @default.
• W2073809314 date "2010-01-01" @default.
• W2073809314 modified "2023-10-18" @default.
• W2073809314 title "CDX2 expression in the intestinal-type gastric epithelial neoplasia: frequency and significance" @default.
• W2073809314 cites W1966483277 @default.
• W2073809314 cites W1982533604 @default.
• W2073809314 cites W1990995790 @default.
• W2073809314 cites W1992581153 @default.
• W2073809314 cites W1994076335 @default.
• W2073809314 cites W1998746607 @default.
• W2073809314 cites W2004761710 @default.
• W2073809314 cites W2014693518 @default.
• W2073809314 cites W2015174770 @default.
• W2073809314 cites W2016207291 @default.
• W2073809314 cites W2021694662 @default.
• W2073809314 cites W2027752363 @default.
• W2073809314 cites W2030946124 @default.
• W2073809314 cites W2052003668 @default.
• W2073809314 cites W2052843262 @default.
• W2073809314 cites W2061130074 @default.
• W2073809314 cites W2065121957 @default.
• W2073809314 cites W2067438558 @default.
• W2073809314 cites W2076988304 @default.
• W2073809314 cites W2088461591 @default.
• W2073809314 cites W2089453598 @default.
• W2073809314 cites W2100538070 @default.
• W2073809314 cites W2107942420 @default.
• W2073809314 cites W2148614508 @default.
• W2073809314 cites W2151439603 @default.
• W2073809314 cites W2338576041 @default.
• W2073809314 doi "https://doi.org/10.1038/modpathol.2009.135" @default.
• W2073809314 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19820687" @default.
• W2073809314 hasPublicationYear "2010" @default.
• W2073809314 type Work @default.
• W2073809314 sameAs 2073809314 @default.
• W2073809314 citedByCount "73" @default.
• W2073809314 countsByYear W20738093142012 @default.
• W2073809314 countsByYear W20738093142013 @default.
• W2073809314 countsByYear W20738093142014 @default.
• W2073809314 countsByYear W20738093142015 @default.
• W2073809314 countsByYear W20738093142016 @default.
• W2073809314 countsByYear W20738093142017 @default.
• W2073809314 countsByYear W20738093142018 @default.
• W2073809314 countsByYear W20738093142019 @default.
• W2073809314 countsByYear W20738093142020 @default.
• W2073809314 countsByYear W20738093142021 @default.
• W2073809314 countsByYear W20738093142022 @default.
• W2073809314 countsByYear W20738093142023 @default.
• W2073809314 crossrefType "journal-article" @default.
• W2073809314 hasAuthorship W2073809314A5001550885 @default.
• W2073809314 hasAuthorship W2073809314A5031405252 @default.
• W2073809314 hasAuthorship W2073809314A5035763230 @default.
• W2073809314 hasAuthorship W2073809314A5038972103 @default.
• W2073809314 hasAuthorship W2073809314A5045555694 @default.
• W2073809314 hasAuthorship W2073809314A5048031696 @default.
• W2073809314 hasAuthorship W2073809314A5059888326 @default.
• W2073809314 hasAuthorship W2073809314A5072389805 @default.
• W2073809314 hasBestOaLocation W20738093141 @default.
• W2073809314 hasConcept C104317684 @default.
• W2073809314 hasConcept C121587040 @default.
• W2073809314 hasConcept C121608353 @default.
• W2073809314 hasConcept C126322002 @default.
• W2073809314 hasConcept C127716648 @default.
• W2073809314 hasConcept C131364181 @default.
• W2073809314 hasConcept C142724271 @default.
• W2073809314 hasConcept C150194340 @default.
• W2073809314 hasConcept C179264091 @default.
• W2073809314 hasConcept C204232928 @default.
• W2073809314 hasConcept C2775894508 @default.
• W2073809314 hasConcept C2776497702 @default.
• W2073809314 hasConcept C2777116383 @default.
• W2073809314 hasConcept C2779422922 @default.
• W2073809314 hasConcept C2781182431 @default.
• W2073809314 hasConcept C2781443798 @default.
• W2073809314 hasConcept C502942594 @default.
• W2073809314 hasConcept C55493867 @default.
• W2073809314 hasConcept C71924100 @default.
• W2073809314 hasConcept C86339819 @default.
• W2073809314 hasConcept C86803240 @default.
• W2073809314 hasConcept C90378955 @default.
• W2073809314 hasConceptScore W2073809314C104317684 @default.
• W2073809314 hasConceptScore W2073809314C121587040 @default.
• W2073809314 hasConceptScore W2073809314C121608353 @default.
• W2073809314 hasConceptScore W2073809314C126322002 @default.
• W2073809314 hasConceptScore W2073809314C127716648 @default.
• W2073809314 hasConceptScore W2073809314C131364181 @default.
• W2073809314 hasConceptScore W2073809314C142724271 @default.
• W2073809314 hasConceptScore W2073809314C150194340 @default.
• W2073809314 hasConceptScore W2073809314C179264091 @default.

• next