FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073836633> ?p ?o ?g. }

• W2073836633 abstract "Large conductance calcium-activated potassium channel (BKCa) plays an important role in the control of uterine contractility during pregnancy. The change from uterine quiescence to enhanced contractile activity may be associated with the spatial and temporal expression of BKCa within myometrium. The objectives of this study were to examine the expression of BKCa alpha- and beta-subunit in upper segment (US) and lower segment (LS) regions of uterus, and to investigate for the possibly differential expression of these proteins in US and LS myometrium obtained from three functional states: (1) non-pregnant (NP); (2) term pregnant not in labour (TNL) and (3) term pregnant in labour (TL).Myometrial biopsies were collected from non-pregnant women at hysterectomy and pregnant women at either elective caesarean section or emergency caesarean section. Protein expression level and cellular localization of BKCa alpha- and beta-subunit in US and LS myometrium were determined by Western blot analysis and immunohistochemistry, respectively.BKCa alpha- and beta-subunit were predominantly localized to myometrial smooth muscle in both US and LS myometrium obtained from non-pregnant and pregnant patients. The level of BKCa alpha-subunit in US but not in LS was significantly higher in NP myometrium than those measured in myometrium obtained during pregnancy. Lower expression of BKCa alpha-subunit in both US and LS was found in TL than in TNL biopsies. Expression of beta-subunit in both US and LS myometrium was significantly reduced in TL group compared with those measured in TNL group. There was no significant difference in BKCa beta-subunit expression in either US or LS between NP and TNL group.Our results suggest that expression of BKCa alpha- and beta-subunit in pregnant myometrium is reduced during labour, which is consistent with the myometrial activity at the onset of parturition." @default.
• W2073836633 created "2016-06-24" @default.
• W2073836633 creator A5008242506 @default.
• W2073836633 creator A5010458663 @default.
• W2073836633 creator A5029469010 @default.
• W2073836633 creator A5062415019 @default.
• W2073836633 date "2009-04-05" @default.
• W2073836633 modified "2023-10-05" @default.
• W2073836633 title "Expression of the calcium-activated potassium channel in upper and lower segment human myometrium during pregnancy and parturition" @default.
• W2073836633 cites W1519345480 @default.
• W2073836633 cites W196263068 @default.
• W2073836633 cites W1971169490 @default.
• W2073836633 cites W1979151401 @default.
• W2073836633 cites W1980297415 @default.
• W2073836633 cites W1982557352 @default.
• W2073836633 cites W1982611822 @default.
• W2073836633 cites W1986967129 @default.
• W2073836633 cites W1987431351 @default.
• W2073836633 cites W2002406387 @default.
• W2073836633 cites W2004180956 @default.
• W2073836633 cites W2006398589 @default.
• W2073836633 cites W2010110485 @default.
• W2073836633 cites W2025444913 @default.
• W2073836633 cites W2046062811 @default.
• W2073836633 cites W2065549861 @default.
• W2073836633 cites W2071860803 @default.
• W2073836633 cites W2091387113 @default.
• W2073836633 cites W2101636692 @default.
• W2073836633 cites W2132250719 @default.
• W2073836633 cites W2160122479 @default.
• W2073836633 cites W2161350899 @default.
• W2073836633 cites W2170346278 @default.
• W2073836633 cites W2336547101 @default.
• W2073836633 cites W2337054849 @default.
• W2073836633 cites W4235879209 @default.
• W2073836633 cites W4236395061 @default.
• W2073836633 cites W50496392 @default.
• W2073836633 doi "https://doi.org/10.1186/1477-7827-7-27" @default.
• W2073836633 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2670306" @default.
• W2073836633 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19344525" @default.
• W2073836633 hasPublicationYear "2009" @default.
• W2073836633 type Work @default.
• W2073836633 sameAs 2073836633 @default.
• W2073836633 citedByCount "28" @default.
• W2073836633 countsByYear W20738366332012 @default.
• W2073836633 countsByYear W20738366332013 @default.
• W2073836633 countsByYear W20738366332014 @default.
• W2073836633 countsByYear W20738366332015 @default.
• W2073836633 countsByYear W20738366332016 @default.
• W2073836633 countsByYear W20738366332018 @default.
• W2073836633 countsByYear W20738366332019 @default.
• W2073836633 countsByYear W20738366332020 @default.
• W2073836633 countsByYear W20738366332022 @default.
• W2073836633 countsByYear W20738366332023 @default.
• W2073836633 crossrefType "journal-article" @default.
• W2073836633 hasAuthorship W2073836633A5008242506 @default.
• W2073836633 hasAuthorship W2073836633A5010458663 @default.
• W2073836633 hasAuthorship W2073836633A5029469010 @default.
• W2073836633 hasAuthorship W2073836633A5062415019 @default.
• W2073836633 hasBestOaLocation W20738366331 @default.
• W2073836633 hasConcept C104317684 @default.
• W2073836633 hasConcept C126322002 @default.
• W2073836633 hasConcept C134018914 @default.
• W2073836633 hasConcept C16685009 @default.
• W2073836633 hasConcept C172680121 @default.
• W2073836633 hasConcept C2776415932 @default.
• W2073836633 hasConcept C2776953305 @default.
• W2073836633 hasConcept C2778164554 @default.
• W2073836633 hasConcept C2779066055 @default.
• W2073836633 hasConcept C2779234561 @default.
• W2073836633 hasConcept C54355233 @default.
• W2073836633 hasConcept C55493867 @default.
• W2073836633 hasConcept C71924100 @default.
• W2073836633 hasConcept C86803240 @default.
• W2073836633 hasConceptScore W2073836633C104317684 @default.
• W2073836633 hasConceptScore W2073836633C126322002 @default.
• W2073836633 hasConceptScore W2073836633C134018914 @default.
• W2073836633 hasConceptScore W2073836633C16685009 @default.
• W2073836633 hasConceptScore W2073836633C172680121 @default.
• W2073836633 hasConceptScore W2073836633C2776415932 @default.
• W2073836633 hasConceptScore W2073836633C2776953305 @default.
• W2073836633 hasConceptScore W2073836633C2778164554 @default.
• W2073836633 hasConceptScore W2073836633C2779066055 @default.
• W2073836633 hasConceptScore W2073836633C2779234561 @default.
• W2073836633 hasConceptScore W2073836633C54355233 @default.
• W2073836633 hasConceptScore W2073836633C55493867 @default.
• W2073836633 hasConceptScore W2073836633C71924100 @default.
• W2073836633 hasConceptScore W2073836633C86803240 @default.
• W2073836633 hasIssue "1" @default.
• W2073836633 hasLocation W20738366331 @default.
• W2073836633 hasLocation W20738366332 @default.
• W2073836633 hasLocation W20738366333 @default.
• W2073836633 hasLocation W20738366334 @default.
• W2073836633 hasOpenAccess W2073836633 @default.
• W2073836633 hasPrimaryLocation W20738366331 @default.
• W2073836633 hasRelatedWork W1969419739 @default.
• W2073836633 hasRelatedWork W1997007826 @default.
• W2073836633 hasRelatedWork W1997328419 @default.
• W2073836633 hasRelatedWork W2023079616 @default.
• W2073836633 hasRelatedWork W2068976714 @default.

• next