FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073887509> ?p ?o ?g. }

• W2073887509 endingPage "3540" @default.
• W2073887509 startingPage "3535" @default.
• W2073887509 abstract "The objective of the present study was to investigate whether ultrasound combined with microbubbles induces apoptotic cell death in androgen-independent prostate cancer cells and to identify the probable mechanism. We used ultrasound in continuous wave mode with a frequency of 21 kHz and a spatial-average temporal-average intensity of 46 mW/cm2. Ultrasound combined with microbubbles (200 μL SonoVue™) was used to treat androgen-independent human prostate cancer PC-3 cells for 30 s. PC-3 cells were divided into three groups: the control group, the ultrasound group and the ultrasound combined with microbubbles group. Immediately after treatment, trypan blue exclusion was used to assess cell viability. Cell apoptosis at 24 h after treatment was measured using transmission electron microscopy and flow cytometry. Western blotting was used to evaluate the expression of the apoptosis-related proteins, Bcl-2 and Bax. Ultrasound combined with microbubbles had a minimal effect on the viability of PC-3 cells and induced minimal levels of cell lysis. The level of apoptosis in PC-3 cells induced by this modality was significantly higher than in controls (12.77 ± 0.31% vs. 2.56 ± 0.22%, P<0.01). Treatment with ultrasound combined with microbubbles increased the expression of Bax, a pro-apoptotic protein, and decreased the expression of Bcl-2, an anti-apoptotic protein. It was concluded that ultrasound combined with microbubbles induces apoptotic cell death in human prostate cancer PC-3 cells through down-regulation of Bcl-2 and up-regulation of Bax." @default.
• W2073887509 created "2016-06-24" @default.
• W2073887509 creator A5010417032 @default.
• W2073887509 creator A5023640343 @default.
• W2073887509 creator A5034331707 @default.
• W2073887509 creator A5055650536 @default.
• W2073887509 creator A5063517774 @default.
• W2073887509 creator A5089156895 @default.
• W2073887509 date "2013-05-23" @default.
• W2073887509 modified "2023-10-16" @default.
• W2073887509 title "Treatment of PC-3 cells with ultrasound combined with microbubbles induces distinct alterations in the expression of Bcl-2 and Bax" @default.
• W2073887509 cites W1547300732 @default.
• W2073887509 cites W1598719623 @default.
• W2073887509 cites W1854461626 @default.
• W2073887509 cites W1944663803 @default.
• W2073887509 cites W1971870473 @default.
• W2073887509 cites W1977295323 @default.
• W2073887509 cites W1992875452 @default.
• W2073887509 cites W1998476614 @default.
• W2073887509 cites W2002702282 @default.
• W2073887509 cites W2014019501 @default.
• W2073887509 cites W2019429201 @default.
• W2073887509 cites W2032808032 @default.
• W2073887509 cites W2040979877 @default.
• W2073887509 cites W2041604464 @default.
• W2073887509 cites W2042353102 @default.
• W2073887509 cites W2042910708 @default.
• W2073887509 cites W2047688825 @default.
• W2073887509 cites W2056472091 @default.
• W2073887509 cites W2058591356 @default.
• W2073887509 cites W2071037802 @default.
• W2073887509 cites W2075576299 @default.
• W2073887509 cites W2099322971 @default.
• W2073887509 cites W2100460679 @default.
• W2073887509 cites W2109894363 @default.
• W2073887509 cites W2112471324 @default.
• W2073887509 cites W2113691798 @default.
• W2073887509 cites W2123187805 @default.
• W2073887509 cites W2158734599 @default.
• W2073887509 doi "https://doi.org/10.1007/s11434-013-5753-y" @default.
• W2073887509 hasPublicationYear "2013" @default.
• W2073887509 type Work @default.
• W2073887509 sameAs 2073887509 @default.
• W2073887509 citedByCount "3" @default.
• W2073887509 countsByYear W20738875092014 @default.
• W2073887509 countsByYear W20738875092015 @default.
• W2073887509 countsByYear W20738875092021 @default.
• W2073887509 crossrefType "journal-article" @default.
• W2073887509 hasAuthorship W2073887509A5010417032 @default.
• W2073887509 hasAuthorship W2073887509A5023640343 @default.
• W2073887509 hasAuthorship W2073887509A5034331707 @default.
• W2073887509 hasAuthorship W2073887509A5055650536 @default.
• W2073887509 hasAuthorship W2073887509A5063517774 @default.
• W2073887509 hasAuthorship W2073887509A5089156895 @default.
• W2073887509 hasBestOaLocation W20738875091 @default.
• W2073887509 hasConcept C121608353 @default.
• W2073887509 hasConcept C126322002 @default.
• W2073887509 hasConcept C126838900 @default.
• W2073887509 hasConcept C143753070 @default.
• W2073887509 hasConcept C1491633281 @default.
• W2073887509 hasConcept C153911025 @default.
• W2073887509 hasConcept C185592680 @default.
• W2073887509 hasConcept C190283241 @default.
• W2073887509 hasConcept C2780070996 @default.
• W2073887509 hasConcept C2780192828 @default.
• W2073887509 hasConcept C31573885 @default.
• W2073887509 hasConcept C502942594 @default.
• W2073887509 hasConcept C53227056 @default.
• W2073887509 hasConcept C553184892 @default.
• W2073887509 hasConcept C55493867 @default.
• W2073887509 hasConcept C64012434 @default.
• W2073887509 hasConcept C71924100 @default.
• W2073887509 hasConcept C86803240 @default.
• W2073887509 hasConceptScore W2073887509C121608353 @default.
• W2073887509 hasConceptScore W2073887509C126322002 @default.
• W2073887509 hasConceptScore W2073887509C126838900 @default.
• W2073887509 hasConceptScore W2073887509C143753070 @default.
• W2073887509 hasConceptScore W2073887509C1491633281 @default.
• W2073887509 hasConceptScore W2073887509C153911025 @default.
• W2073887509 hasConceptScore W2073887509C185592680 @default.
• W2073887509 hasConceptScore W2073887509C190283241 @default.
• W2073887509 hasConceptScore W2073887509C2780070996 @default.
• W2073887509 hasConceptScore W2073887509C2780192828 @default.
• W2073887509 hasConceptScore W2073887509C31573885 @default.
• W2073887509 hasConceptScore W2073887509C502942594 @default.
• W2073887509 hasConceptScore W2073887509C53227056 @default.
• W2073887509 hasConceptScore W2073887509C553184892 @default.
• W2073887509 hasConceptScore W2073887509C55493867 @default.
• W2073887509 hasConceptScore W2073887509C64012434 @default.
• W2073887509 hasConceptScore W2073887509C71924100 @default.
• W2073887509 hasConceptScore W2073887509C86803240 @default.
• W2073887509 hasIssue "28-29" @default.
• W2073887509 hasLocation W20738875091 @default.
• W2073887509 hasOpenAccess W2073887509 @default.
• W2073887509 hasPrimaryLocation W20738875091 @default.
• W2073887509 hasRelatedWork W1991867446 @default.
• W2073887509 hasRelatedWork W2106564520 @default.
• W2073887509 hasRelatedWork W2182837698 @default.

• next