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• W2073889968 abstract "Addition of high concentrations of KC1 to preparations of rat brain synaptosomes incubated with either glucose or pyruvate caused a transient stimulation of oxygen uptake. This increased respiration was insensitive to 1 mM ouabain and 10 microM ruthenium red but was dependent upon the presence of calcium. With 40 mM KCl in the incubation medium, the levels of high-energy phosphate compounds in the synaptosomes were unaltered, whereas pyridine nucleotides underwent a rapid, albeit small and temporary, oxidation. It is postulated that there is a calcium-dependent mechanism in synaptosomes through which the function of the mitochondrial respiratory chain or of oxidative phosphorylation is stimulated directly without the involvement of either adenine nucleotides or mitochondrial dehydrogenases." @default.
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• W2073889968 date "1991-09-01" @default.
• W2073889968 modified "2023-09-27" @default.
• W2073889968 title "Depolarization-induced changes in cellular energy production." @default.
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• W2073889968 doi "https://doi.org/10.1073/pnas.88.17.7600" @default.
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