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- W2073904787 abstract "Novel thin-film oscillator biosensors are developed using picosecond ultrasound method. 100-nm silicon-nitride thin films and 16-nm Pt thin films are used, and ultrashort light pulses are focused on their surfaces to excite the through-thickness resonance vibrations, which are detected by the delayed probe-light pulses using the optoelastic effect. Their fundamental resonance frequencies are 45 and 132 GHz, corresponding to theoretical mass sensitivities of 5.0 × 10−5 and 2.2 × 10−5 pg/cm2/Hz, respectively. These thin-film biosensors are used for detecting human immunoglobulin G (hIgG) with staphylococcus aureus protein A nonspecifically immobilized on the film surfaces. Injection of a 5 nM analyte caused 2% decrease in the resonance frequency." @default.
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- W2073904787 date "2010-12-01" @default.
- W2073904787 modified "2023-09-24" @default.
- W2073904787 title "Ultrathin-film oscillator biosensors excited by ultrafast light pulses" @default.
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- W2073904787 doi "https://doi.org/10.1016/j.bios.2010.06.074" @default.
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