FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073909080> ?p ?o ?g. }

• W2073909080 endingPage "e69601" @default.
• W2073909080 startingPage "e69601" @default.
• W2073909080 abstract "Background More than two-thirds of the world's HIV-positive individuals live in sub-Saharan Africa, where genetic susceptibility to kidney disease is high and resources for kidney disease screening and antiretroviral therapy (ART) toxicity monitoring are limited. Equations to estimate glomerular filtration rate (GFR) from serum creatinine were derived in Western populations and may be less accurate in this population. Methods We compared results from published GFR estimating equations with a direct measure of GFR by iohexol clearance in 99 HIV-infected, ART-naïve Kenyan adults. Iohexol concentration was measured from dried blood spots on filter paper. The bias ratio (mean of the ratio of estimated to measured GFR) and accuracy (percentage of estimates within 30% of the measured GFR) were calculated. Results The median age was 35 years, and 60% were women. The majority had asymptomatic HIV, with median CD4+ cell count of 355 cells/mm3. Median measured GFR was 115 mL/min/1.73 m2. Overall accuracy was highest for the Chronic Kidney Disease Epidemiology Consortium (CKD-EPI) equation. Consistent with a prior report, bias and accuracy were improved by eliminating the coefficient for black race (85% of estimates within 30% of measured GFR). Accuracy of all equations was poor in participants with GFR 60–90 mL/min/1.73 m2 (<65% of estimates within 30% of measured GFR), although this subgroup was too small to reach definitive conclusions. Conclusions Overall accuracy was highest for the CKD-EPI equation. Eliminating the coefficient for race further improved performance. Future studies are needed to determine the most accurate GFR estimate for use in individuals with GFR <90 mL/min/1.73 m2, in whom accurate estimation of kidney function is important to guide drug dosing. Direct measurement of GFR by iohexol clearance using a filter paper based assay is feasible for research purposes in resource-limited settings, and could be used to develop more accurate GFR estimates in African populations." @default.
• W2073909080 created "2016-06-24" @default.
• W2073909080 creator A5005797929 @default.
• W2073909080 creator A5006143217 @default.
• W2073909080 creator A5008326132 @default.
• W2073909080 creator A5024622118 @default.
• W2073909080 creator A5033563716 @default.
• W2073909080 creator A5038897978 @default.
• W2073909080 creator A5042834426 @default.
• W2073909080 creator A5042875116 @default.
• W2073909080 creator A5065762919 @default.
• W2073909080 creator A5069786648 @default.
• W2073909080 creator A5084477412 @default.
• W2073909080 creator A5086666030 @default.
• W2073909080 date "2013-08-08" @default.
• W2073909080 modified "2023-10-10" @default.
• W2073909080 title "Estimating Kidney Function in HIV-Infected Adults in Kenya: Comparison to a Direct Measure of Glomerular Filtration Rate by Iohexol Clearance" @default.
• W2073909080 cites W1497170016 @default.
• W2073909080 cites W1550111394 @default.
• W2073909080 cites W1960255425 @default.
• W2073909080 cites W1967879506 @default.
• W2073909080 cites W2002573731 @default.
• W2073909080 cites W2013123055 @default.
• W2073909080 cites W2031101509 @default.
• W2073909080 cites W2032174302 @default.
• W2073909080 cites W2050071170 @default.
• W2073909080 cites W2052067260 @default.
• W2073909080 cites W2055864845 @default.
• W2073909080 cites W2068837792 @default.
• W2073909080 cites W2080152031 @default.
• W2073909080 cites W2093971642 @default.
• W2073909080 cites W2102136130 @default.
• W2073909080 cites W2104238997 @default.
• W2073909080 cites W2106367406 @default.
• W2073909080 cites W2107778681 @default.
• W2073909080 cites W2109014754 @default.
• W2073909080 cites W2112867103 @default.
• W2073909080 cites W2121965895 @default.
• W2073909080 cites W2122855609 @default.
• W2073909080 cites W2124641083 @default.
• W2073909080 cites W2126835755 @default.
• W2073909080 cites W2136871445 @default.
• W2073909080 cites W2140009647 @default.
• W2073909080 cites W2148107958 @default.
• W2073909080 cites W2148745148 @default.
• W2073909080 cites W2150585325 @default.
• W2073909080 cites W2152470009 @default.
• W2073909080 cites W2155965977 @default.
• W2073909080 cites W2168035113 @default.
• W2073909080 cites W2313051027 @default.
• W2073909080 doi "https://doi.org/10.1371/journal.pone.0069601" @default.
• W2073909080 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3738577" @default.
• W2073909080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23950899" @default.
• W2073909080 hasPublicationYear "2013" @default.
• W2073909080 type Work @default.
• W2073909080 sameAs 2073909080 @default.
• W2073909080 citedByCount "53" @default.
• W2073909080 countsByYear W20739090802013 @default.
• W2073909080 countsByYear W20739090802014 @default.
• W2073909080 countsByYear W20739090802015 @default.
• W2073909080 countsByYear W20739090802016 @default.
• W2073909080 countsByYear W20739090802017 @default.
• W2073909080 countsByYear W20739090802018 @default.
• W2073909080 countsByYear W20739090802019 @default.
• W2073909080 countsByYear W20739090802020 @default.
• W2073909080 countsByYear W20739090802021 @default.
• W2073909080 countsByYear W20739090802022 @default.
• W2073909080 countsByYear W20739090802023 @default.
• W2073909080 crossrefType "journal-article" @default.
• W2073909080 hasAuthorship W2073909080A5005797929 @default.
• W2073909080 hasAuthorship W2073909080A5006143217 @default.
• W2073909080 hasAuthorship W2073909080A5008326132 @default.
• W2073909080 hasAuthorship W2073909080A5024622118 @default.
• W2073909080 hasAuthorship W2073909080A5033563716 @default.
• W2073909080 hasAuthorship W2073909080A5038897978 @default.
• W2073909080 hasAuthorship W2073909080A5042834426 @default.
• W2073909080 hasAuthorship W2073909080A5042875116 @default.
• W2073909080 hasAuthorship W2073909080A5065762919 @default.
• W2073909080 hasAuthorship W2073909080A5069786648 @default.
• W2073909080 hasAuthorship W2073909080A5084477412 @default.
• W2073909080 hasAuthorship W2073909080A5086666030 @default.
• W2073909080 hasBestOaLocation W20739090801 @default.
• W2073909080 hasConcept C126322002 @default.
• W2073909080 hasConcept C126894567 @default.
• W2073909080 hasConcept C134018914 @default.
• W2073909080 hasConcept C159641895 @default.
• W2073909080 hasConcept C2777910003 @default.
• W2073909080 hasConcept C2778653478 @default.
• W2073909080 hasConcept C2779093167 @default.
• W2073909080 hasConcept C2780306776 @default.
• W2073909080 hasConcept C2908647359 @default.
• W2073909080 hasConcept C71924100 @default.
• W2073909080 hasConcept C99454951 @default.
• W2073909080 hasConceptScore W2073909080C126322002 @default.
• W2073909080 hasConceptScore W2073909080C126894567 @default.
• W2073909080 hasConceptScore W2073909080C134018914 @default.
• W2073909080 hasConceptScore W2073909080C159641895 @default.
• W2073909080 hasConceptScore W2073909080C2777910003 @default.

• next