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- W2073931279 abstract "Abstract This article compiles our results in the field of flavonoid chemistry with the aim to synthesise isotopically labelled products. Two strategies (C 6 + C 3 –C 6 vs C 6 –C 2 + C 1 –C 6 ) and some organometallic (Pd 0 , Mo IV ) couplings were explored to build the C 6 –C 3 –C 6 flavonoid skeleton. Following this work, the gram scale has been reached in addition to the asymmetry of the targeted natural flavan-3-ols, i.e. (+)-catechin, (–)-epicatechin, and (–)-procyanidin B3. These characteristics were necessary in the event of using these molecules for pharmacokinetic and metabolic studies in human beings." @default.
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- W2073931279 date "2002-08-01" @default.
- W2073931279 modified "2023-09-27" @default.
- W2073931279 title "Total synthesis of asymmetric flavonoids: the development and applications of 13C-labelling" @default.
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- W2073931279 doi "https://doi.org/10.1016/s1631-0748(02)01417-0" @default.
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