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• W2073942014 abstract "Surface coils are widely used to study in vivo biochemistry by NMR spectroscopy. For inhomogeneous samples, the coil geometry and pulse sequence parameters have to be chosen by taking into account both signal-to-noise ratio and spatial localization of the signal. For the usual single-pulse sequences the position of maximum sensitivity and the spatial selectivity are dependent upon the spin-lattice relaxation time T1. This is source of difficulty with samples containing biochemical species with different relaxation times. It can be palliated by using a long repetition time Tr ⪸ 2-̊3T1 but at the cost of degraded signal-to-noise ratio. The use of the saturation-recovery method provides the same spatial selectivity as a single-pulse sequence with Tr ⪸ 2−3T1 but with better sensitivity. Furthermore the position of the maximum sensitivity surface is not dependent on the spin-lattice relaxation time. The saturation-recovery method can also be used to improve sensitivity with depth pulses, spin-echo techniques, or rotating-frame imaging." @default.
• W2073942014 created "2016-06-24" @default.
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• W2073942014 date "1985-02-01" @default.
• W2073942014 modified "2023-10-16" @default.
• W2073942014 title "Signal to noise and spatial localization of NMR spectra with a surface coil and the saturation-recovery sequence" @default.
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• W2073942014 doi "https://doi.org/10.1016/0022-2364(85)90182-9" @default.
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