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• W2073944304 abstract "Since biofilms are an important issue in the fields of medicine and health, several recent microbiological studies have focused on their formation and their contribution to toxic compound resistance mechanisms. In this review, we describe how metals impact biofilm formation and resistance, and how biofilms can help cells resist toxic metals. First, the organic matrix acts as a barrier isolating the cells from many environmental stresses. Secondly, the metabolism of the cells changes, and a slowly-growing or non-growing sub-population of cells known as persisters emerges. Thirdly, in the case of multispecies biofilms, metabolic interactions are developed, allowing cells to be more persistent or to have greater capacity to survive than a single species biofilm. Finally, we discuss how the high density of the cells may promote horizontal gene transfer processes, resulting in the acquisition of new features. All these crucial mechanisms enable microorganisms to survive and colonize toxic environments, and probably accelerate ongoing evolutionary processes." @default.
• W2073944304 created "2016-06-24" @default.
• W2073944304 creator A5039654452 @default.
• W2073944304 creator A5062610521 @default.
• W2073944304 creator A5080954233 @default.
• W2073944304 creator A5091726617 @default.
• W2073944304 date "2015-12-01" @default.
• W2073944304 modified "2023-10-18" @default.
• W2073944304 title "Toxic metal resistance in biofilms: diversity of microbial responses and their evolution" @default.
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• W2073944304 doi "https://doi.org/10.1016/j.resmic.2015.03.008" @default.
• W2073944304 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25869223" @default.
• W2073944304 hasPublicationYear "2015" @default.
• W2073944304 type Work @default.

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