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- W2073987317 abstract "Helping patients with major depressive disorder achieve symptom-free remission with antidepressant therapy remains challenging. In this activity, 3 investigators discuss the results of a 2-trial, multicenter, randomized, double-blind, placebo-controlled study of adjunctive l-methylfolate, the bioavailable form of folate, in patients who had inadequately responded to an SSRI. The efficacy of doses of 7.5 mg/d versus 15 mg/d is examined, and the safety and tolerability of l-methylfolate are compared with those of other adjunctive treatments. Different types of folate are explained, and the characteristics of patients who might benefit from adjunctive l-methylfolate are proposed." @default.
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- W2073987317 date "2011-08-15" @default.
- W2073987317 modified "2023-10-18" @default.
- W2073987317 title "Evidence for the Use of<scp>L</scp>-Methylfolate Combined With Antidepressants in MDD" @default.
- W2073987317 doi "https://doi.org/10.4088/jcp.11012tx1c" @default.
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