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• W2074000766 abstract "Ia+ immature malignant monocyte clones were isolated from retrovirus-induced lymphomas. These lymphomas contained a predominant population of Ly-1+ T cells. In order to explain this anomaly, the functional capacity of one of these clones, ORA I-a, was assessed. The results indicated that ORA I-a could present protein antigen to syngeneic and semisyngeneic antigenprimed lymph node T cells. Allogeneic stimulation, however, could not be induced. Furthermore, ORA I-a-conditioned medium could augment mitogen-dependent and -independent thymocyte proliferation. These studies suggest that the unique populations of malignant antigen-presenting cells can interact with distinct T-cell subpopulations. Functional analyses of these tumor cell lines may thus be useful in elucidating some of the cellular interactions which occur during the course of immunity." @default.
• W2074000766 created "2016-06-24" @default.
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• W2074000766 creator A5015644777 @default.
• W2074000766 date "1984-03-01" @default.
• W2074000766 modified "2023-10-18" @default.
• W2074000766 title "Induction of T-cell proliferation by an la+ monocytic tumor clone" @default.
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• W2074000766 doi "https://doi.org/10.1016/0008-8749(84)90075-3" @default.
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