FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074001888> ?p ?o ?g. }

• W2074001888 endingPage "185" @default.
• W2074001888 startingPage "177" @default.
• W2074001888 abstract "Abstract A water extract of raw garlic (RGE) and two organosulfur compounds, diallyl sulfide and S‐allylcysteine (SAC), were evaluated for their relative effectiveness in reducing benzo[a]pyrene (BaP)‐DNA adduct formation in stimulated human peripheral blood lymphocytes in vitro. In replicate experiments, RGE significantly inhibited BaP‐DNA adduct formation at concentrations of 0.001, 0.01, and 0.1 mg/ml. SAC also significantly decreased BaP‐DNA adduct formation at concentrations of 0.01 and 0.1 mg/ml. For diallyl sulfide, no significant reduction in BaP‐DNA adduct formation was found. BaP‐DNA adduct formation was not associated with cell viability or proliferation of peripheral blood lymphocytes after the various treatments. No clear scavenging activity was detected for the garlic constituents. Aryl hydrocarbon hydroxylase activity was not decreased, nor was formation of sulfate and glucuronide conjugates of 3‐hydroxy‐BaP increased in the presence of RGE and SAC, indicating that increased glutathione S‐transferase activity or a more efficient repair of BaP‐DNA adducts may explain the observed effects. In addition, reactive oxygen species‐induced 8‐oxodeoxyguanosine in DNA was reduced in the presence of SAC. It is concluded that raw garlic and SAC may be useful in the prevention of BaP‐associated tu‐morigenesis and that further evaluation of their preventive potential in humans at risk appears feasible." @default.
• W2074001888 created "2016-06-24" @default.
• W2074001888 creator A5000452924 @default.
• W2074001888 creator A5004714015 @default.
• W2074001888 creator A5018186238 @default.
• W2074001888 creator A5055885747 @default.
• W2074001888 creator A5056648936 @default.
• W2074001888 creator A5065921950 @default.
• W2074001888 date "1997-01-01" @default.
• W2074001888 modified "2023-10-16" @default.
• W2074001888 title "Reducing effects of garlic constituents on DNA adduct formation in human lymphocytes<i>in vitro</i>" @default.
• W2074001888 cites W1967848926 @default.
• W2074001888 cites W1968406884 @default.
• W2074001888 cites W1971583785 @default.
• W2074001888 cites W1978871110 @default.
• W2074001888 cites W1985088903 @default.
• W2074001888 cites W1988325178 @default.
• W2074001888 cites W1989167941 @default.
• W2074001888 cites W1998082912 @default.
• W2074001888 cites W2000882478 @default.
• W2074001888 cites W2008061525 @default.
• W2074001888 cites W2009878632 @default.
• W2074001888 cites W2012955594 @default.
• W2074001888 cites W2013121887 @default.
• W2074001888 cites W2013612688 @default.
• W2074001888 cites W2014331070 @default.
• W2074001888 cites W2020641997 @default.
• W2074001888 cites W2026676069 @default.
• W2074001888 cites W2036193061 @default.
• W2074001888 cites W2044726035 @default.
• W2074001888 cites W2048264971 @default.
• W2074001888 cites W2048521311 @default.
• W2074001888 cites W2050316877 @default.
• W2074001888 cites W2050703121 @default.
• W2074001888 cites W2058164136 @default.
• W2074001888 cites W2060562628 @default.
• W2074001888 cites W2063263116 @default.
• W2074001888 cites W2070690652 @default.
• W2074001888 cites W2071239116 @default.
• W2074001888 cites W2072096288 @default.
• W2074001888 cites W2074709112 @default.
• W2074001888 cites W2085896858 @default.
• W2074001888 cites W2086371971 @default.
• W2074001888 cites W2108512476 @default.
• W2074001888 cites W2128442121 @default.
• W2074001888 cites W2129776012 @default.
• W2074001888 cites W2131287037 @default.
• W2074001888 cites W2135126854 @default.
• W2074001888 cites W2143660140 @default.
• W2074001888 cites W2143801297 @default.
• W2074001888 cites W2155717658 @default.
• W2074001888 cites W2169954195 @default.
• W2074001888 cites W2198797235 @default.
• W2074001888 cites W85678799 @default.
• W2074001888 doi "https://doi.org/10.1080/01635589709514522" @default.
• W2074001888 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9121947" @default.
• W2074001888 hasPublicationYear "1997" @default.
• W2074001888 type Work @default.
• W2074001888 sameAs 2074001888 @default.
• W2074001888 citedByCount "33" @default.
• W2074001888 countsByYear W20740018882012 @default.
• W2074001888 countsByYear W20740018882014 @default.
• W2074001888 countsByYear W20740018882015 @default.
• W2074001888 countsByYear W20740018882016 @default.
• W2074001888 countsByYear W20740018882017 @default.
• W2074001888 countsByYear W20740018882019 @default.
• W2074001888 countsByYear W20740018882021 @default.
• W2074001888 crossrefType "journal-article" @default.
• W2074001888 hasAuthorship W2074001888A5000452924 @default.
• W2074001888 hasAuthorship W2074001888A5004714015 @default.
• W2074001888 hasAuthorship W2074001888A5018186238 @default.
• W2074001888 hasAuthorship W2074001888A5055885747 @default.
• W2074001888 hasAuthorship W2074001888A5056648936 @default.
• W2074001888 hasAuthorship W2074001888A5065921950 @default.
• W2074001888 hasConcept C108204754 @default.
• W2074001888 hasConcept C114246631 @default.
• W2074001888 hasConcept C153911025 @default.
• W2074001888 hasConcept C178790620 @default.
• W2074001888 hasConcept C181199279 @default.
• W2074001888 hasConcept C185592680 @default.
• W2074001888 hasConcept C202751555 @default.
• W2074001888 hasConcept C2777538855 @default.
• W2074001888 hasConcept C2778951431 @default.
• W2074001888 hasConcept C538909803 @default.
• W2074001888 hasConcept C552990157 @default.
• W2074001888 hasConcept C55493867 @default.
• W2074001888 hasConcept C86803240 @default.
• W2074001888 hasConceptScore W2074001888C108204754 @default.
• W2074001888 hasConceptScore W2074001888C114246631 @default.
• W2074001888 hasConceptScore W2074001888C153911025 @default.
• W2074001888 hasConceptScore W2074001888C178790620 @default.
• W2074001888 hasConceptScore W2074001888C181199279 @default.
• W2074001888 hasConceptScore W2074001888C185592680 @default.
• W2074001888 hasConceptScore W2074001888C202751555 @default.
• W2074001888 hasConceptScore W2074001888C2777538855 @default.
• W2074001888 hasConceptScore W2074001888C2778951431 @default.
• W2074001888 hasConceptScore W2074001888C538909803 @default.
• W2074001888 hasConceptScore W2074001888C552990157 @default.

• next