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- W2074002381 abstract "Despite being a curable disease, tuberculosis (TB) killed more people in 2009 than during any previous year in history. Progress in TB research has been slow, and remains burdened by important gaps in our knowledge of the basic biology of Mycobacterium tuberculosis, the causative agent of TB, and its interaction with the human host. Fortunately, major systems biology initiatives have recently been launched that will help fill some of these gaps. However, to fully comprehend TB and control this disease globally, current systems biological approaches will not suffice. The influence of host and pathogen diversity, changes in human demography, and socioeconomic and environmental factors will also need to be considered. Such a multidisciplinary approach might be best described as ‘systems epidemiology’ in an effort to overcome the traditional boundaries between basic biology and classical epidemiology. Despite being a curable disease, tuberculosis (TB) killed more people in 2009 than during any previous year in history. Progress in TB research has been slow, and remains burdened by important gaps in our knowledge of the basic biology of Mycobacterium tuberculosis, the causative agent of TB, and its interaction with the human host. Fortunately, major systems biology initiatives have recently been launched that will help fill some of these gaps. However, to fully comprehend TB and control this disease globally, current systems biological approaches will not suffice. The influence of host and pathogen diversity, changes in human demography, and socioeconomic and environmental factors will also need to be considered. Such a multidisciplinary approach might be best described as ‘systems epidemiology’ in an effort to overcome the traditional boundaries between basic biology and classical epidemiology." @default.
- W2074002381 created "2016-06-24" @default.
- W2074002381 creator A5072542589 @default.
- W2074002381 creator A5081756586 @default.
- W2074002381 date "2011-10-01" @default.
- W2074002381 modified "2023-10-14" @default.
- W2074002381 title "A role for systems epidemiology in tuberculosis research" @default.
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- W2074002381 doi "https://doi.org/10.1016/j.tim.2011.07.002" @default.
- W2074002381 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3184389" @default.
- W2074002381 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21831640" @default.
- W2074002381 hasPublicationYear "2011" @default.
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